217565

Bariumchlorid Dihydrat

ACS reagent, ≥99%

• Empirische Formel (Hill-System): BaCl₂ · 2H₂O
• CAS-Nummer: 10326-27-9
• Molekulargewicht: 244.26
• EG-Nummer: 233-788-1
• MDL-Nummer: MFCD00149154
• UNSPSC-Code: 12352302
• PubChem Substanz-ID: 329752201
• NACRES: NB.24

Eigenschaften

• Qualität: ACS reagent
• Qualitätsniveau: 200
• Assay: ≥99%
• Form: powder, crystals or chunks
• Verunreinigungen: ≤0.005% insolubles; ≤0.005% oxidizers
• Verlust: 14.0-16.0% loss on drying
• pH-Wert: 5.2-8.2 (25 °C, 5%)
• Kationenspuren: Ca: ≤0.05%; Fe: ≤2 ppm; K: ≤0.0025%; Na: ≤0.005%; Sr: ≤0.1%; heavy metals: ≤5 ppm (by ICP-OES)
• SMILES String: O.O.Cl[Ba]Cl
• InChI: 1S/Ba.2ClH.2H2O/h;2*1H;2*1H2/q+2;;;;/p-2
• InChIKey: PWHCIQQGOQTFAE-UHFFFAOYSA-L

Beschreibung

Anwendung

Barium chloride dihydrate has been used:

• in patch-clamp electrophysiological studies to block subthreshold-activated potassium channels
• as an inward rectifier potassium (Kir) channel blocker to study the role of the channel by measuring the microglial membrane currents in response to voltage ramp stimuli after ATP injection
• to prepare the stock solution to make artificial cerebrospinal fluid (aCSF)

Biochem./physiol. Wirkung

Barium chloride is a potassium ion channel blocker. It is considered toxic. Barium chloride prevents the D2-like receptor-mediated hyperpolarisation of spinal central pattern generator (CPG) neurons

Sicherheitshinweise

• Piktogramme: GHS06
• Signalwort: Danger
• H-Sätze: H301,H319,H332
• P-Sätze: P261 - P264 - P271 - P301 + P310 - P304 + P340 + P312 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Eye Irrit. 2
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable