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Y0000902

Racecadotril für die Peakidentifizierung

European Pharmacopoeia (EP) Reference Standard

Synonym(e):

Racecadotril

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About This Item

Empirische Formel (Hill-System):
C21H23NO4S
CAS-Nummer:
Molekulargewicht:
385.48
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

pharmaceutical primary standard

API-Familie

racecadotril

Hersteller/Markenname

EDQM

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-8°C

SMILES String

CC(=O)SCC(Cc1ccccc1)C(=O)NCC(=O)OCc2ccccc2

InChI

1S/C21H23NO4S/c1-16(23)27-15-19(12-17-8-4-2-5-9-17)21(25)22-13-20(24)26-14-18-10-6-3-7-11-18/h2-11,19H,12-15H2,1H3,(H,22,25)

InChIKey

ODUOJXZPIYUATO-UHFFFAOYSA-N

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Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Racecadotril for peak identification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem./physiol. Wirkung

Racecadotril is a neutral endopeptidase inhibitor, an antidiarrheal drug which acts as a peripherally acting enkephalinase inhibitor.

Verpackung

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Sonstige Hinweise

Sales restrictions may apply.

Ähnliches Produkt

Piktogramme

Exclamation markEnvironment

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Acute Tox. 4 Oral - Aquatic Acute 1

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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J I Emparanza Knörr et al.
Anales de pediatria (Barcelona, Spain : 2003), 69(5), 432-438 (2009-01-09)
To estimate, through a systematic review of the literature, the efficacy of racecadotril in the treatment of acute diarrhoea. Randomised trials carried out in children comparing racecadotril with placebo in terms of diarrhoea recovery, stools output and adverse effects were
Ramón Tormo et al.
Acta paediatrica (Oslo, Norway : 1992), 97(8), 1008-1015 (2008-05-09)
In developing countries acute infectious diarrhoea remains one of the leading causes of death among young children, especially those under 1 year of age. In contrast, in industrialized nations the death rate is very low, although the disease is an
J M Lecomte
International journal of antimicrobial agents, 14(1), 81-87 (2000-03-16)
Since preclinical studies had indicated the potential efficacy and tolerability of racecadotril for the treatment of diarrhoea in man, a series of studies was carried out to assess the clinical effects of racecadotril. These studies were also designed to evaluate
S Huighebaert et al.
Digestive diseases and sciences, 48(2), 239-250 (2003-03-20)
Racecadotril is an enkephalinase inhibitor, presented as a purely antisecretory agent with advantages over the opiate-receptor agonist loperamide in the treatment of diarrhea. A critical review of the literature and the models used was performed. Although pretreatment with high doses
H Szajewska et al.
Alimentary pharmacology & therapeutics, 26(6), 807-813 (2007-09-05)
Racecadotril (acetorphan) is an antisecretory drug that exerts its antidiarrhoeal effects by inhibiting intestinal enkephalinase. To summarize studies testing the efficacy and safety of racecadotril for treating children with acute gastroenteritis. Reports were gathered by searching electronic databases MEDLINE, EMBASE

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