SMB00958

N-Desmethyl imatinib

≥95%

• Synonym(e): N-(4-Methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)-4-(piperazin-1-ylmethyl)benzamide, N-Desmethylimatinib, N-[4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-4-(1-piperazinylmethyl)benzamide, CGP74588, Desmethyl Gleevec, Norimatinib
• Empirische Formel (Hill-System): C₂₈H₂₉N₇O
• CAS-Nummer: 404844-02-6
• Molekulargewicht: 479.58
• UNSPSC-Code: 12352205
• NACRES: NA.77

Eigenschaften

• Biologische Quelle: synthetic
• Qualitätsniveau: 200
• Qualität: research grade
• Assay: ≥95%
• Form: solid
• Mol-Gew.: 479.58 g/mol
• Lagerbedingungen: (Tightly closed. Dry. Keep in a well -ventilated place. Keep locked up or in an area accessible only to qualified or authorized persons.)
• Methode(n): HPLC: suitable
• Löslichkeit: ethanol: 0.20 mg/mL; DMF: 16 mg/mL
• Lagertemp.: 2-8°C
• InChI: 1S/C28H29N7O/c1-20-4-9-24(17-26(20)34-28-31-12-10-25(33-28)23-3-2-11-30-18-23)32-27(36)22-7-5-21(6-8-22)19-35-15-13-29-14-16-35/h2-12,17-18,29H,13-16,19H2,1H3,(H,32,36)(H,31,33,34)
• InChIKey: BQQYXPHRXIZMDM-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

N-Desmethyl imatinib is a pharmacologically active metabolite of imatinib with long elimination half-life. Imatinib is metabolized to N-desmethyl imatinib by CYPs 3A4 and 2C8.

Anwendung

Application: Metabolomics research

Sonstige Hinweise

For additional information on our range of Biochemicals, please complete this form.

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Danger
• H-Sätze: H341,H351,H360D,H362
• P-Sätze: P201 - P202 - P260 - P263 - P264 - P308 + P313
• Gefahreneinstufungen: Carc. 2 - Lact. - Muta. 2 - Repr. 1B
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable