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D0100000

Dapson

European Pharmacopoeia (EP) Reference Standard

Synonym(e):

4-Aminophenylsulfon, 4,4′-Diaminodiphenylsulfon, 4,4′-Sulfonyldianilin, Bis-(4-aminophenyl)-sulfon, DDS, Dapson

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About This Item

Lineare Formel:
(H2NC6H4)2SO2
CAS-Nummer:
80-08-0
Molekulargewicht:
248.30
Beilstein:
788055
MDL-Nummer:
MFCD00007887
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329798581
NACRES:
NA.24

Qualität

pharmaceutical primary standard

Agentur

EP Reference Standard

API-Familie

dapsone

Hersteller/Markenname

EDQM

mp (Schmelzpunkt)

175-177 °C (lit.)

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-8°C

SMILES String

Nc1ccc(cc1)S(=O)(=O)c2ccc(N)cc2

InChI

1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2

InChIKey

MQJKPEGWNLWLTK-UHFFFAOYSA-N

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Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Dapsone EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Verpackung

Dieses Produkt wird, wie von der entsprechenden Pharmakopöe geliefert, angeboten. Die aktuellen Mengeneinheiten finden Sie im Referenzsubstanzen-Katalog der EDQM.

Sonstige Hinweise

Sales restrictions may apply.

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Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 4 Oral - Aquatic Chronic 2 - Repr. 1B - STOT RE 2 - STOT SE 2

Zielorgane

Blood, Blood,spleen,Liver

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number

Leider sind derzeit keine COAs für dieses Produkt online verfügbar.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Mira Stotland et al.
American journal of clinical dermatology, 10(4), 221-227 (2009-06-06)
Dapsone, a synthetic sulfone that has been available for over 60 years, has been used to treat a myriad of cutaneous disorders. Prior to the general acceptance of isotretinoin, oral dapsone had been reported to be effective in the treatment
Amanda Pickert et al.
Expert opinion on pharmacotherapy, 10(9), 1515-1521 (2009-06-10)
Oral dapsone has been available for over 60 years. Its first clinical use was discovered in 1945, when it was found to be efficacious in inhibiting the progression of leprosy. The combined antibacterial and anti-inflammatory pharmacologic activities of dapsone have
R E Kast et al.
British journal of neurosurgery, 26(6), 813-817 (2012-05-04)
Lopez-Gomez et al. recently published remarkable but mechanistically unexplained empirical evidence that the old antibiotic dapsone has antiepileptic activity. We addressed the question "Why should a sulfone antibiotic reduce seizures?". We report here our conclusions based on data from past
Maria Lorenz et al.
Acta dermato-venereologica, 92(2), 194-199 (2012-02-07)
Dapsone is widely used in the treatment of leprosy and several chronic inflammatory dermatological conditions. Hypersensitivity reactions to dapsone are potentially fatal adverse drug reactions with unknown prevalence and risk factors. We performed a systematic review covering all reported cases
Jennifer Tan et al.
Journal of cutaneous medicine and surgery, 10(2), 92-95 (2007-01-24)
Mesotherapy is a procedure involving the injection of substances into the dermis and subcutaneous tissue. Used in Europe for decades in the treatment of various medical conditions and cosmetic fat dissolution, the technique only recently became widely available in the
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