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Merck

63175

Sigma-Aldrich

4-Maleinimido-buttersäure-N-succinimidylester

≥98.0% (HPLC)

Synonym(e):

GMBS, N-(γ-Maleinimidobutyryloxy)-succinimid, N-Succinimidyl-4-maleinimido-butyrat

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About This Item

Empirische Formel (Hill-System):
C12H12N2O6
CAS-Nummer:
Molekulargewicht:
280.23
Beilstein:
6427689
MDL-Nummer:
UNSPSC-Code:
12352106
PubChem Substanz-ID:
NACRES:
NA.25

Qualitätsniveau

Assay

≥98.0% (HPLC)

Eignung der Reaktion

reagent type: linker

mp (Schmelzpunkt)

123-129 °C

Funktionelle Gruppe

NHS ester

Lagertemp.

2-8°C

SMILES String

O=C1N(CCCC(ON2C(CCC2=O)=O)=O)C(C=C1)=O

InChI

1S/C12H12N2O6/c15-8-3-4-9(16)13(8)7-1-2-12(19)20-14-10(17)5-6-11(14)18/h3-4H,1-2,5-7H2

InChIKey

PVGATNRYUYNBHO-UHFFFAOYSA-N

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Anwendung

A heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Second coupling specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 6.8 (6.5-7.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates. Provides a 7-atom linker.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves


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