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Merck

34042

Supelco

Rafoxanid

PESTANAL®, analytical standard

Synonym(e):

3′-Chlor-4′-(4-chlorphenoxy)-3,5-diiodsalicylanilid

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About This Item

Empirische Formel (Hill-System):
C19H11Cl2I2NO3
CAS-Nummer:
Molekulargewicht:
626.01
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

Produktlinie

PESTANAL®

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

agriculture
environmental

Format

neat

SMILES String

Oc1c(I)cc(I)cc1C(=O)Nc2ccc(Oc3ccc(Cl)cc3)c(Cl)c2

InChI

1S/C19H11Cl2I2NO3/c20-10-1-4-13(5-2-10)27-17-6-3-12(9-15(17)21)24-19(26)14-7-11(22)8-16(23)18(14)25/h1-9,25H,(H,24,26)

InChIKey

NEMNPWINWMHUMR-UHFFFAOYSA-N

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Verwandte Kategorien

Allgemeine Beschreibung

Rafoxanide is a halogenated salicylanilide and an anthelmintic agent. It is widely used against fasciolosis and haemonchosis in sheep and cattle. It also finds applications as an adulticide for Fasciola hepatica and Fasciola gigantica.

Anwendung

Rafoxanide may be used as a reference standard in the determination of rafoxanide in plasma and tissue samples using high-performance liquid chromatography (HPLC) coupled with an ultraviolet detector and thermospray − mass spectrometry.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Empfohlene Produkte

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Rechtliche Hinweise

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Analysenzertifikate (COA)

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R M Waruiru et al.
Veterinary parasitology, 75(2-3), 191-197 (1998-06-24)
The anthelmintic efficacy of benzimidazoles, levamisole, rafoxanide and ivermectin was evaluated on an institutional farm in Kenya using faecal egg count reduction test, larval cultures and a controlled slaughter trial. The results of this study indicated simultaneous resistance of Haemonchus
Veterinary Pharmacology and Therapeutics (2017)
J A Van Wyk et al.
The Onderstepoort journal of veterinary research, 66(4), 273-284 (2000-02-26)
Surveys to determine the prevalence and degree of resistance of Haemonchus spp. of sheep and goats to the available anthelmintics in South Africa indicate that small ruminant production is entering a crisis situation. Three surveys employing the faecal egg count
J A van Wyk et al.
Veterinary parasitology, 72(2), 157-165 (1997-12-24)
We became increasingly concerned about indications of possible substandard efficacy of some generic anthelmintics, particularly after P.C. van Schalkwyk (personal communication, 1990) had found some batches of imported generic products obtained from international brokers to be poorly active, despite apparently
J H Gill et al.
International journal for parasitology, 25(4), 463-470 (1995-04-01)
Avermectin (AVM) inhibition of the development of the free-living stages of Haemonchus contortus has been quantified in an assay in which nematode eggs are placed on an agar matrix containing serial dilutions of a drug in the wells of a

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