22880

Chloracetylchlorid

purum, ≥99.0% (GC)

• Synonym(e): Chloroacetic chloride
• Lineare Formel: ClCH₂COCl
• CAS-Nummer: 79-04-9
• Molekulargewicht: 112.94
• Beilstein: 605439
• EG-Nummer: 201-171-6
• MDL-Nummer: MFCD00000725
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 329752357
• NACRES: NA.22

Eigenschaften

• Dampfdichte: 3.9 (vs air)
• Qualitätsniveau: 200
• Dampfdruck: 60 mmHg ( 41.5 °C)
• Qualität: purum
• Assay: ≥99.0% (GC)
• Form: liquid
• Brechungsindex: n20/D 1.453 (lit.); n20/D 1.453
• bp: 105-106 °C (lit.)
• mp (Schmelzpunkt): −22 °C (lit.)
• Löslichkeit: water: insoluble
• Dichte: 1.419 g/mL at 20 °C; 1.418 g/mL at 25 °C (lit.)
• Funktionelle Gruppe: acyl chloride; chloro
• SMILES String: ClCC(Cl)=O
• InChI: 1S/C2H2Cl2O/c3-1-2(4)5/h1H2
• InChIKey: VGCXGMAHQTYDJK-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Chloroacetyl chloride is an aliphatic acid chloride.

Anwendung

Chloroacetyl chloride may be used to prepare:

• 2-chloro-N-(pyridine-2-yl)acetamide via N-acylation of pyridin-2-amine
• chloroacetyl cellulose by reacting with cellulose in N,N-dimethylformamide
• azetobenzothiazine derivatives by reacting with 1,3-benzothiazines in the presence of a base in refluxing toluene
• 2-chloro-1-(3,5-diaryl-4,5-dihydropyrazol-1-yl)-ethanones by reacting with 3,5-diaryl-4,5-dihydropyrazoles
• chloroacetyl isatins by reacting with isatins under microwave conditions

It acts as a linker during the grafting of pyrimethanil with chitosan.

Chloroacetyl chloride was used in the synthesis of N-hydrazino acetyl-sulphonamides.

Sicherheitshinweise

• Piktogramme: GHS06,GHS08,GHS05,GHS09
• Signalwort: Danger
• H-Sätze: H301 + H311 + H331,H314,H372,H400
• P-Sätze: P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P314
• Gefahreneinstufungen: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Eye Dam. 1 - Skin Corr. 1A - STOT RE 1
• Zielorgane: Lungs
• Zusätzliche Gefahrenhinweise: EUH014,EUH029
• Lagerklassenschlüssel: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): 212.0 °F - closed cup
• Flammpunkt (°C): 100 °C - closed cup
• Persönliche Schutzausrüstung: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter