MAGPMAG-24K

MILLIPLEX^® Mouse Angiogenesis/Growth Factor Magnetic Bead Panel - Cancer Multiplex Assay

for the simultaneous quantification of multiple analytes

• UNSPSC-Code: 12161503
• eCl@ss: 32161000
• NACRES: NA.84

Eigenschaften

• Qualitätsniveau: 200
• Speziesreaktivität: mouse
• Hersteller/Markenname: Milliplex^®
• assay range: accuracy: 90-104%; standard curve range: 1-1,000 pg/mL; (Endothelin-1); standard curve range: 137-100,000 pg/mL; (Follistatin); standard curve range: 137-100,000 pg/mL; (HGF); standard curve range: 137-100,000 pg/mL; (SDF-1); standard curve range: 14-10,000 pg/mL; (IL-1b); standard curve range: 14-10,000 pg/mL; (Leptin); standard curve range: 14-10,000 pg/mL; (MIP-1α); standard curve range: 14-10,000 pg/mL; (sALK-1); standard curve range: 14-10,000 pg/mL; (sCD31/ PECAM-1); standard curve range: 27-20,000 pg/mL; (Angiopoietin-2); standard curve range: 27-20,000 pg/mL; (EGF); standard curve range: 27-20,000 pg/mL; (Endoglin); standard curve range: 27-20,000 pg/mL; (MCP-1); standard curve range: 27-20,000 pg/mL; (VEGF-C); standard curve range: 3-2,000 pg/mL; (PLGF-2); standard curve range: 6-4,000 pg/mL; (TNFα); standard curve range: 6-4,000 pg/mL; (VEGF-A); standard curve range: 69-50,000 pg/mL; (FGF-2/FGF-basic); standard curve range: 69-50,000 pg/mL; (Prolactin); standard curve range: 69-50,000 pg/mL; (VEGF-D); standard curve range: 69-50,000 pg/mL; (sFasL); standard curve range: 7-5,000 pg/mL; (Amphiregulin); standard curve range: 7-5,000 pg/mL; (Betacellulin); standard curve range: 7-5,000 pg/mL; (G-CSF); standard curve range: 7-5,000 pg/mL; (IL-17A); standard curve range: 7-5,000 pg/mL; (IL-6); standard curve range: 7-5,000 pg/mL; (KC/CXCL1)
• Methode(n): multiplexing: suitable
• Nachweisverfahren: fluorometric (Luminex xMAP)
• Versandbedingung: wet ice

Beschreibung

Allgemeine Beschreibung

Angiogenesis, the development of new vascular networks, is a key process in normal growth and development as well as in wound healing, with homeostasis maintained by a delicate balance of angiogenic factors and inhibitors. Consequently, insufficient, or excessive blood vessel growth underlies many diseases, including cardiovascular disease, diabetic ulcers, macular degeneration, and cancer. Angiogenesis plays a significant role in tumor growth and metastasis.

MILLIPLEX^® Mouse Angiogenesis//Growth Factor Panel, is a 24-plex (for serum/plasma) or 27-plex (for cell culture) kit to be used for the simultaneous quantification of the following analytes: Angiopoietin-2, G-CSF, sFasL, sAlk-1, Amphiregulin, Leptin, IL-1b, Betacellulin, EGF, IL-6, Endoglin, Endothelin-1, FGF-2, Follistatin, HGF, PECAM-1, IL-17, PLGF-2, KC, MCP-1, Prolactin, MIP-1a, SDF-1, VEGF-C, VEGF-D, VEGF-A, and TNFα. This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.

The Luminex^® xMAP^® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.

Panel Type: Circulating Cancer

Spezifität

Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.

Anwendung

• Analytes: sALK-1, Amphiregulin, Angiopoietin-2, Betacellulin, sCD31/sPECAM-1, EGF, Endoglin, Endothelin-1, sFasL, FGF-2 (FGF-basic), Follistatin (FST), G-CSF, HGF, IL-1β, IL-6, IL-17A (CTLA8), KC (GRO/CINC-1/CXCL1), Leptin, MCP-1 (CCL2), MIP-1α (CCL3), Placental Growth Factor 2 (PLGF-2), Prolactin, SDF-1 (CXCL12), TNF-α, VEGF-A, VEGF-C, VEGF-D
• NOTE: Angiopoeitin-2, Betacellulin, and PECAM-1 should not be run in serum/plasma samples
• Recommended Sample Type: Mouse serum, plasma or tissue/cell culture supernatants or lysates
• Recommended Sample Dilution: 25 μL per well of diluted serum or plasma; cell/tissue culture samples may require diltion in appropriate control medium
• Assay Run Time: Overnight (16-20 hours) at 2-8°C
• Research Category: Cancer

Leistungsmerkmale und Vorteile

Design your multiplex kit by choosing available analytes within this panel.

Verpackung

Everything you need in a single kit.

Lagerung und Haltbarkeit

Recommended storage for kit components is 2 - 8°C.

Sonstige Hinweise

Please note: Sample Type must be selected when configuring this kit. Angiopoeitin-2, Betacellulin, and PECAM-1 should not be run in serum/plasma samples.

Sensitivity: Refer to kit protocol for sensitivities of individual analytes.

Rechtliche Hinweise

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Piktogramme: GHS08,GHS05,GHS07,GHS09
• Signalwort: Danger
• H-Sätze: H302 + H312 + H332,H317,H318,H373,H411
• P-Sätze: P273 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P314
• Gefahreneinstufungen: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
• Zielorgane: Respiratory Tract
• Lagerklassenschlüssel: 10 - Combustible liquids