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MABT200

Sigma-Aldrich

Anti-COL1A2, clone alpha2CT, Azide Free Antibody

clone alpha2CT, from mouse

Synonym(e):

Annexin A6, 67 kDa calelectrin, Annexin VI, Annexin-6, Calphobindin-II, CPB-II, Lipocortin VI, Protein III, p68, p70

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

Antikörperform

purified antibody

Antikörper-Produkttyp

primary antibodies

Klon

alpha2CT, monoclonal

Speziesreaktivität

human

Methode(n)

activity assay: suitable
immunohistochemistry: suitable

Isotyp

IgAκ

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... ANXA6(309)

Allgemeine Beschreibung

Collagens are major fibrous structural elements of cartilage, tendon, bone, skin, lung, and blood vessels. Type I collagen, a heterotrimer consisting of two α1 chains and one α2 chain, is the most abundant fibrillar collagen. It is preferentially synthesized in bone, skin, and tendon and is the most abundant protein found in these tissues.

Immunogen

Epitope: C-terminus
Linear peptide corresponding to the C-terminus of human Collagen type I alpha 2.

Anwendung

Research Category
Zellstruktur
Research Sub Category
Cytoskelett
Activity Assay Analysis: A representative lot from an independent laboratory inhibits fibrin formation in vitro (Chung, H. J., et al. (2008). J Biol Chem. 283(38):25879-25886.).
Anti-COL1A2 antibody, clone alpha2CT, Azide Free is an antibody against COL1A2 for use in IHC & activity assay.

Qualität

Evaluated by Immunohistochemistry Analysis in human bone tissues.

Immunohistochemistry Analysis: A 1:50 dilution of this antibody detected COL1A2 in human bone tissues.

Zielbeschreibung

125 and 150 kDa calculated

Physikalische Form

Protein L
Format: Purified
Purified mouse monoclonal IgAκ in buffer containing PBS without preservatives.

Lagerung und Haltbarkeit

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Collagen fibril formation. A new target to limit fibrosis.
Chung, Hye Jin, et al.
The Journal of Biological Chemistry, 283, 25879-25886 (2008)

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