Direkt zum Inhalt
Merck
Alle Fotos(1)

Key Documents

MAB2168

Sigma-Aldrich

Anti-Huntingtin Protein Antibody, a.a. 2146-2541, clone HU-2E8

ascites fluid, clone HU-2E8, Chemicon®

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise


About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

Antikörperform

ascites fluid

Antikörper-Produkttyp

primary antibodies

Klon

HU-2E8, monoclonal

Speziesreaktivität

monkey, human

Hersteller/Markenname

Chemicon®

Methode(n)

ELISA: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable

Isotyp

IgG1

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

Spezifität

Reacts with Huntingtin protein from human and monkey. Weak to no reactivity with mouse. Has not been tested on other species.

Immunogen

Epitope: a.a. 2146-2541
Human huntingtin fragment from aa 2146 to 2541 as a fusion protein.

Anwendung

Research Category
Neurowissenschaft
Research Sub Category
Neurodegenerative Krankheiten
Anti-Huntingtin Protein Antibody, a.a. 2146-2541, clone HU-2E8 is an antibody against Huntingtin Protein for use in ELISA, WB, IC, IH(P).
ELISA: 1:500-1:5,000

Western blot: 1:500-1:5,000

Immunohistochemistry on frozen and microwave oven treated paraffin sections

(human tissue): 1:500-1:5,000

Immunocytochemistry on transfected cells: 1:500-1:5,000

Optimal working dilutions must be determined by the end user.

Physikalische Form

Ascites fluid. Liquid, does not contain any preservative.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sie haben nicht das passende Produkt gefunden?  

Probieren Sie unser Produkt-Auswahlhilfe. aus.

Empfehlung

Lagerklassenschlüssel

10 - Combustible liquids

WGK

nwg

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Increased apoptosis, Huntingtin inclusions and altered differentiation in muscle cell cultures from Huntington's disease subjects.
Ciammola, A; Sassone, J; Alberti, L; Meola, G; Mancinelli, E; Russo, MA; Squitieri, F; Silani, V
Cell Death and Differentiation null
Huntingtin distribution among striatal output neurons of normal rat brain
Fusco, F.R. et al.
Neuroscience Letters, 339, 53-56 (2003)
Impaired Ganglioside Metabolism in Huntington's Disease and Neuroprotective Role of GM1.
Maglione V, Marchi P, Di Pardo A, Lingrell S, Horkey M, Tidmarsh E, Sipione S
The Journal of Neuroscience null
Paula A Desplats et al.
Neurobiology of disease, 31(3), 298-308 (2008-07-04)
Transcriptional dysregulation has emerged as a central pathogenic mechanism in Huntington's disease (HD), which is associated with neuropathological changes predominantly in the striatum. Here we demonstrate that expression of Bcl11b (a.k.a. CTIP2), a transcription factor exhibiting highly-enriched localization in adult
F R Fusco et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 19(4), 1189-1202 (1999-02-10)
Immunohistochemistry and single-cell RT-PCR were used to characterize the localization of huntingtin and/or its mRNA in the major types of striatal neurons and in corticostriatal projection neurons in rats. Single-label immunohistochemical studies revealed that striatum contains scattered large neurons rich

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.