CBL52
Anti-Insulin-like Growth Factor-I Antibody, clone M23
clone M23, Chemicon®, from mouse
Synonym(e):
IGF-I
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Alle Fotos(1)
About This Item
UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Empfohlene Produkte
Biologische Quelle
mouse
Qualitätsniveau
100
300
Antikörperform
affinity purified immunoglobulin
Antikörper-Produkttyp
primary antibodies
Klon
M23, monoclonal
Speziesreaktivität
human
Hersteller/Markenname
Chemicon®
Methode(n)
immunohistochemistry: suitable (paraffin)
Isotyp
IgG1
NCBI-Hinterlegungsnummer
UniProt-Hinterlegungsnummer
Versandbedingung
wet ice
Angaben zum Gen
human ... IGF1(3479)
Spezifität
The basic IGF-1-like forms (pl>9.0) showed substantial cross-reactivity, as did rat and mouse sera. Monoclonal antibody BM23 was capable of abolishing the biological activities of IGF-1 in vitro bioassays for insulin-like, mitogenic and sulphation activities.
AFFINITY CONSTANT: The affinity of monoclonal antibody BM23 for IGF-1 was 1 x 10E10 L/mole and the cross reactivities of IGF-2, MSA and porcine insulin were 1%, 0.05% and 0.0001% respectively
AFFINITY CONSTANT: The affinity of monoclonal antibody BM23 for IGF-1 was 1 x 10E10 L/mole and the cross reactivities of IGF-2, MSA and porcine insulin were 1%, 0.05% and 0.0001% respectively
Immunogen
Purified human IGF-1.
Anwendung
Research Category
Zelluläre Signaltransduktion
Zelluläre Signaltransduktion
Research Sub Category
Insulin-/stoffwechselassoziierte Signalübertragung
Insulin-/stoffwechselassoziierte Signalübertragung
Immunohistological staining of tissue sections on frozen or formalin fixed paraffin wax embedded sections
Optimal working dilutions must be determined by the end user.
Optimal working dilutions must be determined by the end user.
This Anti-Insulin-like Growth Factor-I Antibody, clone M23 is validated for use in IH(P) for the detection of Insulin-like Growth Factor-I.
Physikalische Form
Format: Purified
The monoclonal is presented at a concentration of 100μg/1ml in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. We recommend that each laboratory determine an optimum working titre for use in its particular application.
Lagerung und Haltbarkeit
For use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at -20°C.
Rechtliche Hinweise
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Haftungsausschluss
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Lagerklassenschlüssel
12 - Non Combustible Liquids
WGK
WGK 2
Analysenzertifikate (COA)
Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.
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E Maiorano et al.
Applied immunohistochemistry & molecular morphology : AIMM, 8(2), 110-119 (2000-08-11)
Insulin-like growth factor 1 (IGF-1) likely is involved in thyrocyte proliferation via autocrine mechanisms, but limited data are available on its in vivo expression in thyroid neoplasms. This prompted us to explore IGF-1 expression at the protein and mRNA levels
An immunoenzymatic method to measure IGF-1 in milk.
A Guidi, L Castigliego, G Iannone, A Armani, D Gianfaldoni
Veterinary Research Communications null
Hakryul Jo et al.
Molecular and cellular biology, 28(13), 4285-4299 (2008-05-07)
Cancer cells in their respective microenvironments must endure various growth-constraining stresses. Under these conditions, the cancer cell-derived factors are thought to modulate the signaling pathways between cell growth and dormancy. Here, we describe a cancer cell-derived regulatory system that modulates
Y-F Huang et al.
British journal of cancer, 99(7), 1096-1102 (2008-09-11)
This study was aimed to identify the expression and the correlation of insulin-like growth factor-1 (IGF-1) system and their prognostic impacts in cervical cancer. Seventy-two patients with early-stage cervical cancer were eligible. We obtained the serum levels of total IGF-1
Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..
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