ABD51

Anti-BMPR-1A Antibody

from rabbit, purified by affinity chromatography

• Synonym(e): Bone morphogenetic protein receptor type-1A, BMP type-1A receptor, BMPR-1A, Activin receptor-like kinase 3, ALK-3, Serine/threonine-protein kinase receptor R5, SKR5, CD_antigen=CD292
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Aufgereinigt durch: affinity chromatography
• Speziesreaktivität: rat, human, mouse
• Methode(n): western blot: suitable
• NCBI-Hinterlegungsnummer: NP_004320
• UniProt-Hinterlegungsnummer: P36894
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... BMPR1A(657)

Beschreibung

Allgemeine Beschreibung

BMPR-1A (bone morphogenic protein receptor type 1A) signaling is known to be important for inner root sheath differentiation, hair follicle cycling and tooth development. Mutations in BMPR-1A are a common cause of juvenile polyposis syndrome (JPS). BMPR-1A is expressed in a high quantity during the formation of the primary and secondary palate and the loss of BMPR-1A could be a cause for the cleft palate birth defect.

Spezifität

This antibody recognizes BMPR-1A at the extracellular domain.

Immunogen

Epitope: Extracellular domain

KLH-conjugated linear peptide corresponding to the extracellular domain of human BMPR-1A.

Anwendung

Research Category
Stammzellforschung

Research Sub Category
Kinasen & Phosphatasen

Anti-BMPR-1A Antibody is an antibody against BMPR-1A for use in WB.

Qualität

Evaluated by Western Blot in NIH/3T3 cell lysate.

Western Blot Analysis: 0.1 µg/mL of this antibody detected BMPR-1A on 10 µg of NIH/3T3 cell lysate.

Zielbeschreibung

~75 kDa observed. The calculated molecular weight is 67 kDa; however, BMPR-1A has been shown as a ~77 kDa band in western blots (Koenig, B., et al. (1994). Molecular and Cellular Biology. 14(9):5961-5974).

Physikalische Form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Lagerung und Haltbarkeit

Stable for 1 year at 2-8°C from date of receipt.

Hinweis zur Analyse

Control
NIH/3T3 cell lysate

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable