8.52370

ivDde-Lys(Fmoc)-OH

Novabiochem^®

• Synonym(e): N-α-1-(4,4-Dimethyl-2,6-dioxocyclohex-1-ylidene)-3methylbutyl-N-ε-Fmoc-L-lysine
• Empirische Formel (Hill-System): C₃₄H₄₂N₂O₆
• Molekulargewicht: 574.71
• UNSPSC-Code: 12352209

Eigenschaften

• Qualitätsniveau: 200
• Produktlinie: Novabiochem^®
• Form: solid
• Eignung der Reaktion: reaction type: Fmoc solid-phase peptide synthesis
• Hersteller/Markenname: Novabiochem^®
• Anwendung(en): peptide synthesis
• Funktionelle Gruppe: amine
• Lagertemp.: 15-25°C

Beschreibung

Allgemeine Beschreibung

Novel tool for the synthesis of branched, cyclic and modified peptides by Fmoc SPPS. Following introduction of this building block, the Fmoc group can be removed by treatment with piperidine in DMF enabling chain extension on the lysine side chain. Once this is complete, the ivDde group is removed with 2% hydrazine in DMF and the main peptide chain can be extended using normal Fmoc SPPS protocols.

Associated Protocols and Technical Articles
Guide to Selection of Orthogonally-Protected Building Blocks for Fmoc SPPS

Hinweis zur Analyse

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Assay (HPLC, area%): ≥ 97.0 % (a/a)
Purity (TLC(011A)): ≥ 97 %
Solubility (1 mmole in 2 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Rechtliche Hinweise

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable