8.52016

Fmoc-Phe-OH

Novabiochem^®

• Synonym(e): N-α-Fmoc-L-phenylalanine
• Empirische Formel (Hill-System): C₂₄H₂₁NO₄
• CAS-Nummer: 35661-40-6
• Molekulargewicht: 387.43
• MDL-Nummer: MFCD00037128
• UNSPSC-Code: 12352209
• EG-Index-Nummer: 252-661-1
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 400
• Produktlinie: Novabiochem^®
• Assay: ≥98% (TLC); ≥98.0% (acidimetric); ≥99.0% (HPLC)
• Form: powder
• Eignung der Reaktion: reaction type: Fmoc solid-phase peptide synthesis
• Hersteller/Markenname: Novabiochem^®
• mp (Schmelzpunkt): 180-188 °C
• Anwendung(en): peptide synthesis
• Funktionelle Gruppe: Fmoc
• Lagertemp.: 2-30°C
• InChI: 1S/C24H21NO4/c26-23(27)22(14-16-8-2-1-3-9-16)25-24(28)29-15-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21/h1-13,21-22H,14-15H2,(H,25,28)(H,26,27)
• InChIKey: SJVFAHZPLIXNDH-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities.
Standard building block for introduction of phenylalanine amino-acid residues by Fmoc SPPS

Associated Protocols and Technical Articles
Fmoc-amino acids for Peptide Production
Cleavage and Deprotection Protocols for Fmoc SPPS

Anwendung

• Drug release from hydrogels: Utilization in the preparation and optimization of amino acid-based double network hydrogels for photocontrolled drug release, showing promise in drug delivery systems (S Xiang et al., 2024).
• Self-assembling biomaterials: Research on self-assembling Fmoc-Phe-OH peptides for the formation of functional biomaterials, applicable in tissue engineering and regenerative medicine (H Ren et al., 2021).

Verlinkung

Replaces: 04-12-1030

Hinweis zur Analyse

Farbe (visuell): weiß bis fast weiß
Aussehen der Substanz (visuell): Pulver
Farbzahl (0,5 M in DMF): ≤ 150 Hazen
Identität (IR): entspricht
Enantiomerenreinheit: ≥ 99.8 % (a/a)
Reinheit (HPLC): ≥ 99.0 % (a/a)
Fmoc-ß-Ala-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-ß-Ala-Phe-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-Phe-Phe-OH (HPLC): ≤ 0.1 % (a/a)
Gehalt an freier Aminosäure (GC): ≤ 0.2 %
Reinheit (DC(011A)): ≥ 98 %
Reinheit (DC(0811)): ≥ 98 %
Löslichkeit (25 mmol in 50 ml DMF): klar löslich
Gehalt (acidimetrisch): ≥ 98.0 %
Wasser (K. F.): ≤ 2.0 %
Ethylacetat (HS-GC): ≤ 0.5 %
Acetat (IC): ≤ 0.02 %
DC-Bedingungen gemäß den Angaben unseres Hauptkataloges

Rechtliche Hinweise

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable