8.20122

Benzamidine hydrochloride hydrate

for synthesis

• Synonym(e): Benzamidine hydrochloride hydrate
• Empirische Formel (Hill-System): C₇H₈N₂ · xHCl · yH₂O
• CAS-Nummer: 206752-36-5
• Molekulargewicht: 120.15 (anhydrous free base basis)
• MDL-Nummer: MFCD00066285
• UNSPSC-Code: 12352107
• EG-Index-Nummer: 216-795-4
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 200
• Assay: ≥98.5% (HPLC)
• Form: powder
• pH-Wert: 5 (20 °C, 50 g/L in H₂O)
• mp (Schmelzpunkt): 80-84 °C
• Lagertemp.: 2-30°C
• InChI: 1S/C7H8N2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H3,8,9)/p+1
• InChIKey: PXXJHWLDUBFPOL-UHFFFAOYSA-O

Beschreibung

Anwendung

• Intriguing role of water in protein-ligand binding studied by neutron crystallography on trypsin complexes.: This study investigates the interaction of benzamidine hydrochloride hydrate as a serine protease inhibitor, focusing on its binding mechanism in the presence of water molecules. Utilizing neutron crystallography, the research provides insights into the dynamic role of water in enhancing the binding affinity and stability of the inhibitor to trypsin. This understanding is crucial for the design of more effective protease inhibitors in pharmaceutical applications (Schiebel et al., 2018).

Hinweis zur Analyse

Gehalt (HPLC, Fl.%): ≥ 98.5 % (a/a)
Wasser (K. F.): 7.0 - 13.0 %
Identität (IR): entspricht

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable