5.06382

MPTP Hydrochloride

≥98% (TLC), solid, dopaminergic neurotoxin, Calbiochem

• Synonym(e): MPTP Hydrochloride, Dopaminergic neurotoxin, MPTP
• Empirische Formel (Hill-System): C₁₂H₁₅N · xHCl
• CAS-Nummer: 23007-85-4
• Molekulargewicht: 173.25 (free base basis)
• MDL-Nummer: MFCD00012790
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• product name: MPTP Hydrochloride,
• Assay: ≥98% (TLC)
• Qualitätsniveau: 100
• Form: solid
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze; protect from light
• Farbe: white
• Löslichkeit: water: 100 mg/mL
• Lagertemp.: 2-8°C
• InChI: 1S/C12H15N.ClH/c1-13-9-7-12(8-10-13)11-5-3-2-4-6-11;/h2-7H,8-10H2,1H3;1H
• InChIKey: KOWJANGMTAZWDT-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

A neurotoxin that is a precusor of MPP+ which is toxic to dopaminergic neurons and causes Parkinsonism. Widely used in research to induce Parkinson′s disease models in primates.

Warnhinweis

Toxicity: Toxic (F)

Rekonstituierung

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Sonstige Hinweise

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Langston, J. W., et al. 1985. Trends in Neurosci.8, 79.

Gabriel, T. L., et al. 1999. Nature Med.5, 1403.
Zhang, X., et al. 2010. J. Proteome Res.9, 1496.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H301 - H370
• P-Sätze: P260 - P264 - P270 - P301 + P310 - P405 - P501
• Gefahreneinstufungen: Acute Tox. 3 Oral - STOT SE 1
• Zielorgane: Nervous system
• Lagerklassenschlüssel: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3