330200-M

Ecotin, E. coli

A potent, broad range inhibitor of serine proteases.

• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥90% (SDS-PAGE)
• Form: liquid
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze; avoid repeated freeze/thaw cycles
• Lagertemp.: −70°C

Beschreibung

Allgemeine Beschreibung

A potent, broad range inhibitor of serine proteases.

A potent, broad range inhibitor or serine proteases. Exhibits picomolar binding constant for the inhibition of chymotrypsin, elastase, Factor Xa, Factor XIIa, kallikrein, and trypsin. Also an effective inhibitor of collagenase and granzyme B.

Biochem./physiol. Wirkung

Primary Target
serine proteases

Product does not compete with ATP.

Target IC₅₀: 1 pM against serine proteases

binds trypsin in the picomolar range

Verpackung

Please refer to vial label for lot-specific concentration.

Warnhinweis

Toxicity: Standard Handling (A)

Physikalische Form

In 1.0 mM HCl.

Rekonstituierung

Following initial thaw, aliquot and freeze (-70°C).

Sonstige Hinweise

McGrath, M.E., et al. 1995. Protein Sci. 4, 141.
Seong, I.S., et al. 1994. J. Biol. Chem. 269, 21915.
McGrath, M.E., et al. 1991. J. Biol. Chem. 266, 6620.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable