M-128
Mirtazapine solution
1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
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Alle Fotos(1)
About This Item
Empirische Formel (Hill-System):
C17H19N3
CAS-Nummer:
Molekulargewicht:
265.35
EG-Nummer:
UNSPSC-Code:
41116107
NACRES:
NA.24
Empfohlene Produkte
Qualität
certified reference material
Form
liquid
Leistungsmerkmale
Snap-N-Spike®/Snap-N-Shoot®
Verpackung
ampule of 1 mL
Hersteller/Markenname
Cerilliant®
Konzentration
1.0 mg/mL in methanol
Methode(n)
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
Anwendung(en)
clinical testing
Format
single component solution
Lagertemp.
−20°C
SMILES String
CN1CCN2C(C1)c3ccccc3Cc4cccnc24
InChI
1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3
InChIKey
RONZAEMNMFQXRA-UHFFFAOYSA-N
Angaben zum Gen
human ... ADRA2A(150) , ADRA2B(151) , ADRA2C(152) , HTR2A(3356) , HTR2C(3358)
Allgemeine Beschreibung
Mirtazapine is a tetracyclic antidepressant marketed under the trade names Remeron®, Avanza, or Zispin for treatment of depression. This Certified Spiking Solution® is suitable for LC/MS or GC/MS applications in forensic analysis, clinical toxicology, or urine drug testing.
Anwendung
- Mirtazapine research solution for CNS studies: A study on the nose-to-brain delivery of mirtazapine via lipid nanocapsules highlights its potential for enhanced CNS targeting, offering a promising approach for treating neurological conditions. This method aims to improve the bioavailability and therapeutic effectiveness of mirtazapine, showcasing its utility in pharmacokinetic research and CNS depressant studies (Ibrahim et al., 2024).
- Mirtazapine liquid formulation for orally disintegrating tablets: Research into developing a novel direct compressible co-processed excipient for the formulation of mirtazapine orally disintegrating tablets emphasizes its importance in enhancing patient compliance and dosing accuracy. This study demonstrates mirtazapine′s role in pharmaceutical formulations, ensuring rapid onset of action which is critical in acute management of depressive episodes (Loke et al., 2024).
- High-purity mirtazapine liquid for neurotransmitter research: A review linking stress, depression, and insulin resistance explores the systemic effects of chronic inflammation and the role of treatments like mirtazapine. This research underscores the importance of mirtazapine in understanding the biochemical pathways involved in chronic mental health disorders and their somatic comorbidities (Mehdi et al., 2023).
- Stable mirtazapine formulation for opioid withdrawal treatment: Mirtazapine is explored as a one-stop strategy for the treatment of opioid withdrawal symptoms, highlighting its efficacy in reducing withdrawal severity and potentially lowering the dependency on traditional opioid replacement therapies. This application provides insights into mirtazapine′s versatility in treating complex drug dependencies (Lalani et al., 2023).
- Mirtazapine aqueous solution for pharmacokinetic profiling: Research on the simultaneous separation and determination of several chiral antidepressants, including mirtazapine, in wastewater by two-dimensional liquid chromatography offers critical insights into environmental exposure and bioaccumulation risks. This study is pivotal for environmental safety and pharmaceutical dispersion monitoring, reflecting mirtazapine′s impact beyond clinical settings (Zhong et al., 2023).
Rechtliche Hinweise
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Remeron is a registered trademark of MSD
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Ähnliches Produkt
Produkt-Nr.
Beschreibung
Preisangaben
Signalwort
Danger
H-Sätze
Gefahreneinstufungen
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
Zielorgane
Eyes
Lagerklassenschlüssel
3 - Flammable liquids
WGK
WGK 1
Flammpunkt (°F)
49.5 °F - closed cup
Flammpunkt (°C)
9.7 °C - closed cup
Analysenzertifikate (COA)
Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.
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Seda G Sagdinc et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 104, 222-234 (2012-12-26)
Mirtazapine (±)-1,2,3,4,10,14b-hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)(2)benzazepine is a compound with antidepressant therapeutic effects. It is the 6-aza derivative of the tetracyclic antidepressant mianserin (±)-2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine. The FT-IR and FT-Raman spectra of mirtazapine have been recorded in 4000-400 cm(-1) and 3500-10 cm(-1), respectively. The optimized geometry
Xiaoyu Liu et al.
Neurochemical research, 38(9), 1973-1979 (2013-07-10)
Chemotherapic drugs may elicit acute or chronic peripheral neuropathies. Mirtazapine, as an antidepressant, is also used for the treatment of neuropathic pain. The current study aimed to investigate the effect of mirtazapine on the oxaliplatin-induced neuropathy in rats as well
Steven M Graves et al.
Pharmacology & therapeutics, 136(3), 343-353 (2012-09-11)
Understanding substance use disorders (SUDs) and the problems associated with abstinence has grown in recent years. Nonetheless, highly efficacious treatment targeting relapse prevention has remained elusive, and there remains no FDA-approved pharmacotherapy for psychostimulant dependence. Preclinical and clinical investigations assessing
E L Theunissen et al.
Clinical pharmacology and therapeutics, 93(6), 493-501 (2013-04-17)
The aim of this study was to assess the effects of a novel antidepressant, vortioxetine 10 mg, on driving, cognitive, and psychomotor performance in 24 healthy subjects in a double-blind, placebo-controlled, three-way crossover design. Mirtazapine 30 mg was included as an active
Cost-effectiveness analyses for mirtazapine and sertraline in dementia: randomised controlled trial.
Renee Romeo et al.
The British journal of psychiatry : the journal of mental science, 202, 121-128 (2012-12-22)
Depression is a common and costly comorbidity in dementia. There are very few data on the cost-effectiveness of antidepressants for depression in dementia and their effects on carer outcomes. To evaluate the cost-effectiveness of sertraline and mirtazapine compared with placebo
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Analysis of 20 pharmaceutical compounds in calf serum using Supel™ Swift HLB SPE cartridge for cleanup and LC-MS determination and another commercially available HLB cartridge for comparison.
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