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Merck

D-902

Supelco

Diazepam-d5 -Lösung

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirische Formel (Hill-System):
C16D5H8ClN2O
CAS-Nummer:
Molekulargewicht:
289.77
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

certified reference material

Qualitätsniveau

Form

liquid

Leistungsmerkmale

Snap-N-Spike®/Snap-N-Shoot®

Verpackung

ampule of 1 mL

Hersteller/Markenname

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

Konzentration

100 μg/mL in methanol

Methode(n)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Anwendung(en)

clinical testing

Format

single component solution

Lagertemp.

−20°C

SMILES String

O=C1CN=C(C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])C3=C(C=CC(Cl)=C3)N1C

InChI

1S/C16H13ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3/i2D,3D,4D,5D,6D

InChIKey

AAOVKJBEBIDNHE-VIQYUKPQSA-N

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Allgemeine Beschreibung

Diazepam is a benzodiazepine used to treat a number of symptoms from anxiety and panic attacks to insomnia. This stable-labeled internal standard is suited for quantitation of diazepam levels in urine, serum, or plasma by LC/MS or GC/MS for urine drug testing, clinical toxicology, forensic analysis, or isotope dilution methods. Diazepam, a benzodiazpine frequently abused recreationally, is sold under the trade name Valium®.

Anwendung


  • Diazepam-d₅ internal standard: Research on clomiphene in keratinous matrices utilized Diazepam-d₅ as an internal standard in LC-MS/MS analysis, demonstrating its essential role in ensuring precision and reliability in forensic toxicology (Kintz et al., 2023).

  • Stable isotope-labeled Diazepam: A forensic study highlighted the use of Diazepam-d₅ in confirming the presence of drugs in decomposed cadavers, showcasing its importance in providing corroborative evidence in cases of serial homicides (Ottaviano et al., 2021).

  • Diazepam-d₅ for analytical research: The postmortem analysis of benzodiazepines in human bone by gas chromatography-mass spectrometry employed Diazepam-d₅, demonstrating its effectiveness as a reference material for accurate drug quantification (Mancini et al., 2021).

  • Diazepam-d₅ in pharmacological studies: Method development for quantitative determination of statins highlighted the use of Diazepam-d₅ in tandem mass spectrometry, underlining its utility in adherence testing and therapeutic drug monitoring (Wagmann et al., 2020).

  • Diazepam-d₅ in receptor binding studies: An evaluation of benzodiazepines and zolpidem in nails and their stability in chlorinated water demonstrated Diazepam-d₅′s role as a robust analytical standard, critical for ensuring the integrity of pharmacological assays (Moretti et al., 2018).

Rechtliche Hinweise

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Valium is a registered trademark of Roche Products Inc.

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Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Zielorgane

Eyes,Central nervous system

Lagerklassenschlüssel

3 - Flammable liquids

WGK

WGK 2

Flammpunkt (°F)

49.5 °F - closed cup

Flammpunkt (°C)

9.7 °C - closed cup


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