880346P

DChemsPC

Avanti Research^™ - A Croda Brand 880346P, powder

• Synonym(e): 1,2-dicholesterylhemisuccinoyl-sn-glycero-3-phosphocholine
• Empirische Formel (Hill-System): C₇₀H₁₁₆NO₁₂P
• CAS-Nummer: 1155878-69-5
• Molekulargewicht: 1194.64
• UNSPSC-Code: 51191904
• NACRES: NA.25

Eigenschaften

• Form: powder
• Verpackung: pkg of 1 × 25 mg (880346P-25mg)
• Hersteller/Markenname: Avanti Research^™ - A Croda Brand 880346P
• Lipid-Typ: cardiolipins; phospholipids
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: O=P([O-])(OCC[N+](C)(C)C)OC[C@H](OC(CCC(OC1CC[C@]2(C)C(C1)=CCC3C2CC[C@]4(C)C3CC[C@H]4[C@@H](C)CCCC(C)C)=O)=O)COC(CCC(OC5CC[C@]6(C)C(C5)=CCC7C6CC[C@]8(C)C7CC[C@H]8[C@@H](C)CCCC(C)C)=O)=O
• InChI: 1S/C70H116NO12P/c1-46(2)16-14-18-48(5)57-24-26-59-55-22-20-50-42-52(32-36-67(50,7)61(55)34-38-69(57,59)9)81-64(73)29-28-63(72)78-44-54(45-80-84(76,77)79-41-40-71(11,12)13)83-66(75)31-30-65(74)82-53-33-37-68(8)51(43-53)21-23-56-60-27-25-58(49(6)19-15-17-47
• InChIKey: XIHPVFHVRYJTJV-DJTREBHPSA-N

Beschreibung

Anwendung

DChemsPC might be used:

• as a substitute for cholesterol in liposome formulation to study its effect on membrane stability
• in the preparation of pH-gradient liposomes
• to form sterol-phospholipid hybrid with palmitoyl-2-cholesterylhemisuccinoyl-sn-glycero-3-phosphocholine (PCholPC) and to study its properties and interactions

Biochem./physiol. Wirkung

Liposome instability in blood is caused mainly due to cholesterol exchange. Sterol modified phospholipid retains the bilayer-stabilizing effect of free cholesterol, inhibiting its transfer from the bilayer. Therefore, disterolphospholipids are ideal for liposome preparation. The use of DChemsPC in liposomes prevents content leaking into the serum.

Verpackung

5 mL Amber Glass Screw Cap Vial (880346P-25mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3