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Merck

856705P

Avanti

16:0 Lyso PE

Avanti Research - A Croda Brand, powder

Synonym(e):

1-hexadecanoyl-sn-glycero-3-phosphoethanolamine; PE(16:0/0:0); 110698, Lysophosphatidylethanolamine 16:0

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise


About This Item

Empirische Formel (Hill-System):
C21H44NO7P
CAS-Nummer:
Molekulargewicht:
453.55
UNSPSC-Code:
12352211
NACRES:
NA.25

Assay

>99% (LPE; may contain up to 10% of the 2-LPE isomer, TLC)

Form

powder

Verpackung

pkg of 1 × 200 mg (856705P-200mg)
pkg of 1 × 25 mg (856705P-25mg)

Hersteller/Markenname

Avanti Research - A Croda Brand

Lipid-Typ

phospholipids
cardiolipins

Versandbedingung

dry ice

Lagertemp.

−20°C

SMILES String

O[C@](COP([O-])(OCC[NH3+])=O)([H])COC(CCCCCCCCCCCCCCC)=O

Anwendung

16:0 Lyso PE has been used to degranulate human eosinophils. It has also been used to enhance nerve growth factor (NGF)-induced mitogen-activated protein kinase (MAPK) phosphorylation.

Verpackung

5 mL Amber Glass Screw Cap Vial (856705P-200mg)
5 mL Amber Glass Screw Cap Vial (856705P-25mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

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Cellular membranes contain glycerophospholipids, which have important structural and functional roles in cells. Glycerophospholipids are first formed in the de novo pathway (Kennedy pathway) and are matured in the remodeling pathway (Lands' cycle). Recently, lysophospholipid acyltransferases functioning in Lands' cycle
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Triterpenoid saponins from Kuding tea have demonstrated preventive effects on hyperlipidaemia induced by a high-fat diet. Lysoglycerophospholipids (Lyso-GPLs) are known to be associated with proatherogenic conditions such as hyperlipidaemia. In this study, a target profiling strategy based on a multiple
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Lysophosphatidylcholine (LPC) is one of the major lysophospholipids mainly generated by phospholipase A2 (PLA2)-mediated hydrolysis of phosphatidylcholine (PC). We previously found that LPC displays neurotrophin-like activity in the rat pheochromocytoma PC12 cells and in cerebellar granule neurons, but the molecular
Kimberly D Dyer et al.
Journal of immunology (Baltimore, Md. : 1950), 184(11), 6327-6334 (2010-04-28)
Platelet-activating factor (PAF [1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine]) is a phospholipid mediator released from activated macrophages, mast cells, and basophils that promotes pathophysiologic inflammation. Eosinophil responses to PAF are complex and incompletely elucidated. We show in this article that PAF and its 2-deacetylated metabolite

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