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Merck

850325P

Avanti

10:0 PC

1,2-didecanoyl-sn-glycero-3-phosphocholine, powder

Synonym(e):

1,2-dicapryl-sn-glycero-3-phosphocholine; PC(10:0/10:0)

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise


About This Item

Empirische Formel (Hill-System):
C28H56NO8P
CAS-Nummer:
Molekulargewicht:
565.72
UNSPSC-Code:
51191904
NACRES:
NA.25

Assay

>99% (TLC)

Form

powder

Verpackung

pkg of 1 × 200 mg (850325P-200mg)
pkg of 1 × 25 mg (850325P-25mg)

Hersteller/Markenname

Avanti Research - A Croda Brand 850325P

Lipid-Typ

cardiolipins
phospholipids

Versandbedingung

dry ice

Lagertemp.

−20°C

SMILES String

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCC)=O)COC(CCCCCCCCC)=O)=O

InChI

1S/C28H56NO8P/c1-6-8-10-12-14-16-18-20-27(30)34-24-26(25-36-38(32,33)35-23-22-29(3,4)5)37-28(31)21-19-17-15-13-11-9-7-2/h26H,6-25H2,1-5H3

InChIKey

MLKLDGSYMHFAOC-UHFFFAOYSA-N

Allgemeine Beschreibung

10:0 PC (DDPC/1,2-didecanoyl-sn-glycero-3-phosphocholine) is a zwitterionic and shorter-acyl chain phospholipid.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Anwendung

10:0 PC (DDPC/1,2-didecanoyl-sn-glycero-3-phosphocholine) may be used:
  • as an internal standard to measure lipid metabolites for metabolic profiling using hydrophilic interaction liquid chromatography (HILIC)
  • to prepare lipid bilayer to reconstitute Vpu (membrane protein) and for biophysical studies
  • to prepare phospholipid membrane to study lipid-induced conformation of a 27-residue Cry4Ba-α7 peptide

Biochem./physiol. Wirkung

High or low level of phosphatidylcholine (PC) can affect energy metabolism in several organelles.

Verpackung

20 mL Clear Glass Screw Cap Vial (850325P-200mg)
5 mL Clear Glass Sealed Ampule (850325P-25mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Kasorn Tiewsiri et al.
Archives of biochemistry and biophysics, 482(1-2), 17-24 (2008-12-24)
Helix 7 in the Cry4Ba-pore-forming domain contains conserved Tyr(249) and Phe(264) that are crucially involved in mosquito-larvicidal activity. We have now characterized lipid-induced conformation of a 27-residue Cry4Ba-alpha7 peptide in phospholipid membranes using ATR-FTIR and hydrogen/deuterium (H(+)/D(+)) exchange experiments. ATR-FTIR
Chun-Cheih Chao et al.
Cell, 179(7), 1483-1498 (2019-12-10)
Metabolism has been shown to control peripheral immunity, but little is known about its role in central nervous system (CNS) inflammation. Through a combination of proteomic, metabolomic, transcriptomic, and perturbation studies, we found that sphingolipid metabolism in astrocytes triggers the

Artikel

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

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