810604P

16:0-16 Doxyl PC

Avanti Research^™ - A Croda Brand 810604P, powder

• Synonym(e): 1-palmitoyl-2-stearoyl-(16-doxyl)-sn-glycero-3-phosphocholine
• Empirische Formel (Hill-System): C₄₆H₉₀N₂O₁₀P
• CAS-Nummer: 216491-65-5
• Molekulargewicht: 862.19
• UNSPSC-Code: 51321705
• NACRES: NA.25

Eigenschaften

• Assay: >99% (TLC)
• Form: powder
• Verpackung: pkg of 1 × 1 mg (810604P-1mg)
• Hersteller/Markenname: Avanti Research^™ - A Croda Brand 810604P
• Lipid-Typ: ESR probes
• Versandbedingung: dry ice
• Lagertemp.: −20°C

Beschreibung

Allgemeine Beschreibung

Avanti′s nitroxide spin product listing is a group of compounds designed to act as membrane probes. A variety of positions down the hydrophobic chain are labeled with the nitroxide functional groups to allow probing the membrane at various depths. These compounds have been synthesized from 1-palmitoyl-2-hydroxy-sn-glycerol-3-phosphocholine with the product being purified by column chromatography. Various n-doxyl phosphocholines have been recently used as biophysical tools to elucidate membrane trafficking with phosphatidylinositol transfer proteins and as fluorescent quenchers in lipid bilayer structural studies.

Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.

Anwendung

16:0-16 Doxyl PC has been used as a spin probe in electron spin resonance spectroscopy.

Biochem./physiol. Wirkung

Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.

Verpackung

5 mL Clear Glass Sealed Ampule (810604P-1mg)

Angaben zur Herstellung

Product use: To prevent aggregation, prepare water-based solutions of 2 mM stock solutions of n-DOXYL PCs and store in plastic. Dilute stock solutions to 0.03- 0.1 mM solutions for EPR studies. For liposome preparations in fluorescent quenching measurements, dissolve the doxyl lipid in 150 μl absolute ethanol for a concentration of 40.3 mM , Additional supplemental information.

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids