810174P

16:0-12:0 NBD PA

Avanti Polar Lipids 810174P, powder

• Synonym(e): 1-palmitoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphate (ammonium salt)
• Empirische Formel (Hill-System): C₃₇H₆₆N₅O₁₁P
• CAS-Nummer: 474942-96-6
• Molekulargewicht: 787.92
• UNSPSC-Code: 12352211
• NACRES: NA.25

Eigenschaften

• Assay: >99% (TLC)
• Form: powder
• Verpackung: pkg of 1 × 1 mg (810174P-1mg)
• Hersteller/Markenname: Avanti Polar Lipids 810174P
• Versandbedingung: dry ice
• Lagertemp.: −20°C

Beschreibung

Allgemeine Beschreibung

Phosphatidic acid (PA) is a simple anionic cellular glycerophospholipid possessing a phosphomonoester polar head group and two long hydrophobic acyl chains. 7-nitro-2-1,3-benzoxadiazol-4-yl (NBD) PA is a fluorophore labeled phospholipid having 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) at the sn-2 fatty acid of PA.

Anwendung

16:0-12:0 NBD PA or 1-palmitoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphate (ammonium salt) is suitable:

• to incubate cells for the imaging of lyso phosphatidylcholine (PC) in P. falciparum live cells
• as a component of separation buffer for the separation of phosphoinositides and sphingolipids in the microchip devices
• in cytidine diphosphate diacylglycerol (CDP-DAG) synthase activity assay

Biochem./physiol. Wirkung

Phosphatidic acid (PA) influences membrane fusion and membrane fission events and membrane curvature. It acts as a signaling molecule for various cellular processes including membrane trafficking and sperm hyper-activation.

Verpackung

5 mL Amber Glass Screw Cap Vial (810174P-1mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids