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D8402
1,2-Diacetylhydrazin
98%
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About This Item
Lineare Formel:
CH3CONHNHCOCH3
CAS-Nummer:
Molekulargewicht:
116.12
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352100
PubChem Substanz-ID:
NACRES:
NA.22
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Qualitätsniveau
Assay
98%
Form
powder
bp
209 °C/15 mmHg (lit.)
mp (Schmelzpunkt)
138-140 °C (lit.)
SMILES String
CC(=O)NNC(C)=O
InChI
1S/C4H8N2O2/c1-3(7)5-6-4(2)8/h1-2H3,(H,5,7)(H,6,8)
InChIKey
ZLHNYIHIHQEHJQ-UHFFFAOYSA-N
Signalwort
Warning
Gefahreneinstufungen
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Zielorgane
Respiratory system
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
dust mask type N95 (US), Eyeshields, Gloves
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E B Bhalerao et al.
Indian journal of physiology and pharmacology, 29(2), 83-88 (1985-04-01)
Patients suffering from pulmonary tuberculosis were investigated for the levels of isoniazid (INH) and its metabolites viz. acetyl-INH, mono and diacetyl hydrazines and ammonia. It was observed that 50% of the patients are slow inactivators of INH and almost all
S V Bhide et al.
Cancer letters, 23(2), 235-240 (1984-06-01)
Two hydrazine derivatives, monoacetyl hydrazine (MAH) and diacetyl hydrazine (DAH), have been tested for mutagenic response in the Salmonella/mammalian microsome assay and micronucleus test. MAH but not DAH, increased the revertant mutants in TA100 and TA1535 and also increased the
J A Timbrell et al.
Human toxicology, 3(6), 485-495 (1984-12-01)
The urinary metabolite profile of isoniazid has been studied in patients receiving the drug as therapy for tuberculosis and the profile in patients suffering liver damage due to isoniazid compared with that in control patients. There were no consistent differences
E B Bhalerao et al.
Indian journal of physiology and pharmacology, 29(3), 133-138 (1985-07-01)
Effect of isoniazid (INH) and its metabolites e.g. mono and diacetyl hydrazines (MAH and DAH respectively) was studied on circulating and tissue folates in mice (a species susceptible to INH tumorigenicity) and rats (a species resistant to INH carcinogenicity). It
Ramachandran Azhakar et al.
Dalton transactions (Cambridge, England : 2003), 41(5), 1529-1533 (2011-12-14)
The reaction of N-heterocyclic silylene (NHSi) L [L = CH{(C[double bond, length as m-dash]CH(2))(CMe)(2,6-iPr(2)C(6)H(3)N)(2)}Si] with benzoylhydrazine, 1,2-dicarbethoxyhydrazine, 1,2-diacetylhydrazine and 1,2-bis(tert-butoxycarbonyl)hydrazine in 1 : 1 molar ratio resulted in compounds 1-4 with an almost quantitative yield and five coordinate silicon atoms.
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