ALD00422

2-Formylphenyl sulfofluoridate

• Empirische Formel (Hill-System): C₇H₅FO₄S
• Molekulargewicht: 204.18
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 329772674
• NACRES: NA.22

Eigenschaften

• Beschreibung: Fp: >230°F
• Qualitätsniveau: 100
• Form: liquid
• Brechungsindex: n20/D 1.5086
• Dichte: 1.4545 g/mL at 25 °C
• SMILES String: O=S(OC1=C(C=O)C=CC=C1)(F)=O
• InChI: 1S/C7H5FO4S/c8-13(10,11)12-7-4-2-1-3-6(7)5-9/h1-5H
• InChIKey: SUOCJDDQQKVIKZ-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

2-Formylphenyl sulfofluoridate is an aryl fluorosulfate. It can be synthesized from the reaction between phenol and sulfuryl fluoride in the presence of triethylamine. It undergoes Sonogashira coupling reaction with phenyl acetylene.

Anwendung

The following aryl fluorosulfate can be utilized as a cross-coupling partner in Suzuki-Miyaura reactions. The standard reaction conditions for these palladium-catalyzed C-C bond formations are ligand-free and can be performed in water, at room temperature and are not air sensitive.

Sonstige Hinweise

Palladium-Catalyzed, Ligand-Free Suzuki Reaction in Water Using Aryl Fluorosulfates

Sicherheitshinweise

• Piktogramme: GHS05
• Signalwort: Danger
• H-Sätze: H314
• P-Sätze: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Gefahreneinstufungen: Eye Dam. 1 - Skin Corr. 1B
• Lagerklassenschlüssel: 8A - Combustible, corrosive hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): No data available
• Flammpunkt (°C): No data available