930539

(S,R,S)-AHPC-Me-C₅-COOH

≥95%

• Synonym(e): 6-{[(2S)-1-[(2S,4R)-4-Hydroxy-2-{[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]carbamoyl}pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]carbamoyl}hexanoic acid, 7-(((S)-1-((2S, 4R)-4-Hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-7-oxoheptanoic acid, L-Prolinamide, N-(6-carboxy-1-oxohexyl)-3-methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-, (4R)
• Empirische Formel (Hill-System): C₃₀H₄₂N₄O₆S
• CAS-Nummer: 2229976-21-8
• Molekulargewicht: 586.74
• MDL-Nummer: MFCD33029229
• UNSPSC-Code: 12352100
• NACRES: NA.22

Eigenschaften

• ligand: VH032
• Qualitätsniveau: 100
• Assay: ≥95%
• Form: powder
• Funktionelle Gruppe: carboxylic acid
• Lagertemp.: 2-8°C

Beschreibung

Anwendung

(S,R,S)-AHPC-Me-C₅-COOH is a functionalized von-Hippel-Lindau (VHL) ligand with a terminal carboxyl group, allowing rapid conjugation of amine containing linkers. A basic building block for development of a protein degrader library.

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Sonstige Hinweise

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Impact of linker length on the activity of PROTACs

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable