900917

N-Azidoacetylmannosamine-tetraacylated

95%

• Synonym(e): Ac₄ManNAz
• Empirische Formel (Hill-System): C₁₆H₂₂N₄O₁₀
• CAS-Nummer: 361154-30-5
• Molekulargewicht: 430.37
• UNSPSC-Code: 12352116
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 95%
• Form: powder or crystals
• Eignung der Reaktion: reaction type: click chemistry
• Lagertemp.: −20°C

Beschreibung

Anwendung

N-Azidoacetylmannosamine-tetraacylated (Ac₄ManNAz) is an azide-containing metabolic glycoprotein labeling reagent that can be incorporated into the sialic acid biosynthesis pathway. The azide-modified protein can be detected by reaction with alkynes. For example alkynes labeled with a fluorescent probe or a biotin can be used. The acetyl groups increase cell permeability and allow the unnatural sugars to easily pass through the cell membrane. Carboxyesterases remove the acetyl groups once the monosaccharide is in the cell.

Tetraacylated N-azidoacetylmannosamine is generally used in click chemistry applications in bioconjugate chemistry.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable