900683

2-(3-(But-3-yn-1-yl)-3H-diazirin-3-yl)ethan-1-amine

95%

• Synonym(e): Amino diazirine alkyne, Probe building block
• Empirische Formel (Hill-System): C₇H₁₁N₃
• CAS-Nummer: 1450752-97-2
• Molekulargewicht: 137.18
• MDL-Nummer: MFCD29918288
• UNSPSC-Code: 12352116

Eigenschaften

• Qualitätsniveau: 100
• Assay: 95%
• Form: liquid
• Lagertemp.: −20°C
• SMILES String: NCCC1(N=N1)CCC#C
• InChIKey: FMCIBERQJQEYIZ-UHFFFAOYSA-N

Beschreibung

Anwendung

2-(3-(But-3-yn-1-yl)-3H-diazirin-3-yl)ethan-1-amine is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and amine synthetic handle. When appended to a ligand or pharmacophore through its amine linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Sonstige Hinweise

Technology Spotlight: Trifuctional Probe Building Blocks

Design and Synthesis of Minimalist Terminal Alkyne-Containing Diazirine Photo-Crosslinkers and Their Incorporation into Kinase Inhibitors for Cell- and Tissue-Based Proteome Profiling

"Minimalist" Cyclopropene-Containing Photo-Cross-Linkers Suitable for Live-Cell Imaging and Affinity-Based Protein Labeling

Sicherheitshinweise

• Piktogramme: GHS02
• Signalwort: Danger
• H-Sätze: H242
• P-Sätze: P210 - P234 - P235 - P240 - P370 + P378 - P403
• Gefahreneinstufungen: Self-react. C
• Lagerklassenschlüssel: 5.2 - Organic peroxides and self-reacting hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable