640042

4-Amino-1-Boc-Piperidin

97%

• Synonym(e): 1-Boc-4-piperidinamin, 4-Amino-1-piperidincarbonsäure-tert.-butylester
• Empirische Formel (Hill-System): C₁₀H₂₀N₂O₂
• CAS-Nummer: 87120-72-7
• Molekulargewicht: 200.28
• MDL-Nummer: MFCD01076201
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24883073
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 97%
• Form: solid
• SMILES String: CC(C)(C)OC(=O)N1CCC(N)CC1
• InChI: 1S/C10H20N2O2/c1-10(2,3)14-9(13)12-6-4-8(11)5-7-12/h8H,4-7,11H2,1-3H3
• InChIKey: LZRDHSFPLUWYAX-UHFFFAOYSA-N

Beschreibung

Anwendung

Employed in a microwave-assisted solid-phase synthesis of N-substituted piperidines via direct annulation of primary amines with resin-bound dimesylates.

4-Amino-1-Boc-piperidine can be used:

• as a starting material in the synthesis of N-(3-(4-hydroxyphenyl)-propenoyl)-amino acid tryptamides, which can act as silent information regulator human type 2 (SIRT2) inhibitors
• to synthesize piperidine-substituted triazine derivativesand piperidinylamino-diarylpyrimidine (pDAPY) derivatives as potent HIV-1 non-nucleoside reverse transcriptase inhibitors (HIV-1 NNRTIs)

Sicherheitshinweise

• Piktogramme: GHS05,GHS07
• Signalwort: Danger
• H-Sätze: H302,H315,H318,H335
• P-Sätze: P261 - P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Faceshields, Gloves