564494

4-Fluor-2-methoxyphenylborsäure

≥95%

• Synonym(e): 4-Fluoro-2-methoxybenzeneboronic acid
• Lineare Formel: FC₆H₃(OCH₃)B(OH)₂
• CAS-Nummer: 179899-07-1
• Molekulargewicht: 169.95
• MDL-Nummer: MFCD03788423
• UNSPSC-Code: 12352103
• PubChem Substanz-ID: 24880183
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥95%
• Form: powder
• mp (Schmelzpunkt): 131-136 °C (lit.)
• Funktionelle Gruppe: fluoro
• SMILES String: COc1cc(F)ccc1B(O)O
• InChI: 1S/C7H8BFO3/c1-12-7-4-5(9)2-3-6(7)8(10)11/h2-4,10-11H,1H3
• InChIKey: ADJBXDCXYMCCAD-UHFFFAOYSA-N

Beschreibung

Anwendung

Reactant involved in:

• Suzuki-Miyaura cross-coupling reactions for synthesis of heterobiaryls
• Suzuki and Still coupling for synthesis of antithrombotic drugs

Reactant / precursor used for the synthesis of biologically active molecules including:

• 2-(4-pyridyl)thienopyridinones for use as GSK-3β inhibitors
• Arylheteroarylmethylamines as NR2B subtype of NMDA receptor antagonists with antidepressant activity
• Biphenylketones for use as dual modulators of inflammation and bone loss
• CB1 antagonists

Sonstige Hinweise

Contains varying amounts of anhydride

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)