512125

3-Pyridinboronsäure

≥95.0%

• Synonym(e): 3-Pyridinylborsäure
• Empirische Formel (Hill-System): C₅H₆BNO₂
• CAS-Nummer: 1692-25-7
• Molekulargewicht: 122.92
• MDL-Nummer: MFCD00674177
• UNSPSC-Code: 12352103
• PubChem Substanz-ID: 24873612
• NACRES: NA.22

Eigenschaften

• Assay: ≥95.0%
• Form: solid
• mp (Schmelzpunkt): >300 °C (lit.)
• SMILES String: OB(O)c1cccnc1
• InChI: 1S/C5H6BNO2/c8-6(9)5-2-1-3-7-4-5/h1-4,8-9H
• InChIKey: ABMYEXAYWZJVOV-UHFFFAOYSA-N

Beschreibung

Anwendung

3-Pyridinylboronic acid can be used as a reagent for:

• Phosphine-free Suzuki-Miyaura cross-coupling reactions.
• Regioselective Suzuki-Miyaura coupling and tandem palladium-catalyzed intramolecular aminocarbonylation and annulation.
• N-arylation using copper acetylacetonate catalyst.
• Copper-mediated cyanation and regioselective cyanation of electron-rich benzenes.

It can also be used to prepare:

• New linear poly(phenylpyridyl) chains by Suzuki coupling.
• Oligopyridyl foldamers as mimics of a-helix twist.
• Many highly significant therapeutic enzymatic and kinase inhibitors and receptor antagonists.
• Pyridine substituted pyridinium N-(2′-azinyl)aminides by reacting with dibromo pyridinium aminides via Suzuki coupling reaction.

Sonstige Hinweise

Contains varying amounts of anhydride

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)