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270873

Sigma-Aldrich

2-Hydroxychinolin

98%

Synonym(e):

2-Chinolinol, Carbostyril

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About This Item

Empirische Formel (Hill-System):
C9H7NO
CAS-Nummer:
59-31-4
Molekulargewicht:
145.16
EG-Nummer:
200-420-6
MDL-Nummer:
MFCD00006743
UNSPSC-Code:
12352100
PubChem Substanz-ID:
24856409
NACRES:
NA.22

Qualitätsniveau

100

Assay

98%

Form

crystals

mp (Schmelzpunkt)

198-199 °C (lit.)

Löslichkeit

alcohol: soluble(lit.)
diethyl ether: soluble(lit.)
dilute HCl: soluble(lit.)
water: slightly soluble (1 g/950mL)(lit.)

SMILES String

Oc1ccc2ccccc2n1

InChI

1S/C9H7NO/c11-9-6-5-7-3-1-2-4-8(7)10-9/h1-6H,(H,10,11)

InChIKey

LISFMEBWQUVKPJ-UHFFFAOYSA-N

Verwandte Kategorien

Allgemeine Beschreibung

2-Hydroxyquinoline is a specific inhibitor of plaque paraoxonase1 (PON1).

Anwendung

2-Hydroxyquinoline was used to obtain the design of the platinum(IV) complexes with intense bands shifted towards longer wavelengths. The Pt(IV) complexes are inert stable prodrugs that were photoactivated to produce Pt(II) species with promising anticancer activity.

Piktogramme

CorrosionExclamation mark
GHS05,GHS07

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Analysenzertifikate (COA)

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2-Hydroxychinolin-4-Carboxylsäure 97%

Sigma-Aldrich

674869

2-Hydroxychinolin-4-Carboxylsäure

2,4-Chinolindiol 97%

Sigma-Aldrich

Q1336

2,4-Chinolindiol

2-Hydroxy-4-Methylchinolin 97%

Sigma-Aldrich

H43601

2-Hydroxy-4-Methylchinolin

Hui-Chung Tai et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 18(34), 10630-10642 (2012-07-19)
Diazido Pt(IV) complexes are inert stable prodrugs that can be photoactivated to produce Pt(II) species with promising anticancer activity. Our studies of the photochemistry of Pt(IV) complexes, [Pt(X)(2) (Y)(2) (Z)(2) ](0/-1) (X=N-ligands (NH(3) , pyridine, etc.)/S(CH(3) )(2) /H(-) , Y=(pseudo)halogen
Kaitlyn M Ferguson et al.
Frontiers in microbiology, 9, 2190-2190 (2018-10-05)
Objective: The intestinal concentrations of antimicrobial drugs that select for resistance in fecal bacteria of cattle are poorly understood. Our objective was to associate active drug concentrations in the intestine of steers with changes in the resistance profile and composition
Alexander J Bones et al.
Experimental parasitology, 196, 28-37 (2018-12-07)
Cryptosporidium is a genus of single celled parasites capable of infecting a wide range of animals including humans. Cryptosporidium species are members of the phylum apicomplexa, which includes well-known genera such as Plasmodium and Toxoplasma. Cryptosporidium parasites cause a severe
Shirin Biglari et al.
Microbial drug resistance (Larchmont, N.Y.), 23(5), 545-555 (2016-11-18)
Multidrug-resistant (MDR) Acinetobacter baumannii has increasingly emerged as an important nosocomial pathogen. The aim of this study was to determine the resistance profiles and genetic diversity in A. baumannii clinical isolates in a tertiary medical center in Malaysia. The minimum
Antonios Keirouz et al.
Journal of nanobiotechnology, 18(1), 51-51 (2020-03-20)
The state-of-the-art hernia meshes, used in hospitals for hernia repair, are predominantly polymeric textile-based constructs that present high mechanical strength, but lack antimicrobial properties. Consequently, preventing bacterial colonization of implanted prosthetic meshes is of major clinical relevance for patients undergoing
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