250600

Tris(dimethylamino)sulfoniumdifluortrimethylsilikat

technical grade

• Synonym(e): TAS-F, TASF, Tris-(dimethylamino)-schwefel-trimethylsilyldifluorid
• Lineare Formel: [(CH₃)₂N]₃S[(CH₃)₃SiF₂]
• CAS-Nummer: 59218-87-0
• Molekulargewicht: 275.48
• Beilstein: 3577020
• MDL-Nummer: MFCD00012170
• UNSPSC-Code: 12352101
• PubChem Substanz-ID: 24855064
• NACRES: NA.22

Eigenschaften

• Qualität: technical grade
• Eignung der Reaktion: reagent type: reductant
• Lagertemp.: 2-8°C
• SMILES String: C[Si-](C)(C)(F)F.CN(C)[S+](N(C)C)N(C)C
• InChI: 1S/C6H18N3S.C3H9F2Si/c1-7(2)10(8(3)4)9(5)6;1-6(2,3,4)5/h1-6H3;1-3H3/q+1;-1
• InChIKey: JMGVTLYEFSBAGJ-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Tris(dimethylamino)sulfonium difluorotrimethylsilicate is widely used in organic synthesis as a source of fluoride ion for the synthesis of fluorinated compounds by C-F bond formation. It is also used as a reagent in hydrosilylation, cyanomethylation of ketones and Pd-catalyzed cross-coupling reactions.

Anwendung

Tris(dimethylamino)sulfonium difluorotrimethylsilicate (TASF₂SiMe₃) can be used as a mild deprotecting reagent for the cleavage of silicon protecting groups.
It can also be used

• To synthesize deoxyfluoro sugars by reacting with trifluoromethanesulfonyl derivatives of partially protected sugars.
• As a reagent for the fluorination of hydroxyl-containing compounds.

Sonstige Hinweise

Remainder tris(dimethylamino)sulfonium bifluoride

Sicherheitshinweise

• Piktogramme: GHS05
• Signalwort: Danger
• H-Sätze: H314
• P-Sätze: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Gefahreneinstufungen: Skin Corr. 1B
• Zusätzliche Gefahrenhinweise: EUH014
• Lagerklassenschlüssel: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges