159034

Acetohydroxamsäure

98%

• Synonym(e): AHA
• Lineare Formel: CH₃CONHOH
• CAS-Nummer: 546-88-3
• Molekulargewicht: 75.07
• Beilstein: 1739019
• EG-Nummer: 208-913-8
• MDL-Nummer: MFCD00009994
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24849786
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 98%
• mp (Schmelzpunkt): 88-90 °C (lit.)
• Funktionelle Gruppe: amine
• SMILES String: CC(NO)=O
• InChI: 1S/C2H5NO2/c1-2(4)3-5/h5H,1H3,(H,3,4)
• InChIKey: RRUDCFGSUDOHDG-UHFFFAOYSA-N
• Angaben zum Gen: human ... CA2(760) , MMP3(4314)

Beschreibung

Allgemeine Beschreibung

Acetohydroxamic acid is a potent inhibitor of bacterial urease activity and reduces urinary ammonia levels. 2-Acetohydroxamic acid loaded floating microspheres forms an efficient drug delivery system for the treatment of Helicobacter pylori.

Anwendung

Used in urease inhibition studies and for in situ generation of nitrosocarbonylmethane as a Diels-Alder dienophile.

Acetohydroxamic acid was used:

• to study the mechanism of complexation of iron (III) with acetohydroxamic acid
• to study the inhibitory mechanism of lansoprazole and omeprazole on Helicobacter pyloni
• in urease inhibition studies
• for in situ generation of nitrosocarbonylmethane as a Diels-Alder dienophile

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Danger
• H-Sätze: H360
• P-Sätze: P201 - P308 + P313
• Gefahreneinstufungen: Repr. 1B
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type P2 (EN 143) respirator cartridges