158992

Methyl p-Toluensulfonat

98%

• Synonym(e): Methyl p-methylbenzenesulfonate, Methyl toluene-4-sulfonate, Methyl tosylate, Methylp-tosylate
• Lineare Formel: CH₃C₆H₄SO₃CH₃
• CAS-Nummer: 80-48-8
• Molekulargewicht: 186.23
• Beilstein: 609209
• EG-Nummer: 201-283-5
• MDL-Nummer: MFCD00008417
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24849783
• NACRES: NA.22

Eigenschaften

• Dampfdichte: 6.45 (vs air)
• Qualitätsniveau: 200
• Dampfdruck: 1 mmHg ( 20 °C)
• Assay: 98%
• Form: solid
• Selbstzündungstemp.: 896 °F
• Brechungsindex: n20/D 1.5172 (lit.)
• bp: 144-145 °C/5 mmHg (lit.)
• mp (Schmelzpunkt): 25-28 °C (lit.)
• Dichte: 1.234 g/mL at 25 °C (lit.)
• Lagertemp.: 2-8°C
• SMILES String: COS(=O)(=O)c1ccc(C)cc1
• InChI: 1S/C8H10O3S/c1-7-3-5-8(6-4-7)12(9,10)11-2/h3-6H,1-2H3
• InChIKey: VUQUOGPMUUJORT-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Methyl p-toluenesulfonate is sulfonate ester present as potentially genotoxic impurity in drug substances. Kinetics of reactions of methyl p-toluenesulfonate with N,N-dimethylaniline has been investigated. It participates in selective 1-substitution reaction of tetrazole.

Sicherheitshinweise

• Piktogramme: GHS05,GHS07
• Signalwort: Danger
• H-Sätze: H302,H314,H317
• P-Sätze: P260 - P272 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1B
• Lagerklassenschlüssel: 8A - Combustible corrosive hazardous materials
• WGK: WGK 2
• Flammpunkt (°F): 235.4 °F - closed cup
• Flammpunkt (°C): 113 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges