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149225

Sigma-Aldrich

Dipropyldisulfid

98%

Synonym(e):

Propyldisulfid

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About This Item

Lineare Formel:
CH3CH2CH2SSCH2CH2CH3
CAS-Nummer:
629-19-6
Molekulargewicht:
150.31
Beilstein:
969200
EG-Nummer:
211-079-8
MDL-Nummer:
MFCD00009378
UNSPSC-Code:
12352100
PubChem Substanz-ID:
24848938
NACRES:
NA.22

Qualitätsniveau

100

Assay

98%

Form

liquid

Brechungsindex

n20/D 1.497 (lit.)

bp

195-196 °C (lit.)

mp (Schmelzpunkt)

−86 °C (lit.)

Dichte

0.96 g/mL at 25 °C (lit.)

Funktionelle Gruppe

disulfide

SMILES String

CCCSSCCC

InChI

1S/C6H14S2/c1-3-5-7-8-6-4-2/h3-6H2,1-2H3

InChIKey

ALVPFGSHPUPROW-UHFFFAOYSA-N

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Allgemeine Beschreibung

Dipropyl disulfide (DPDS) was an efficient scavenger of reactive oxygen species (ROS) at a lower concentration in both HL-60 and HepG2 cells. It prevents the oxidative DNA damage caused by N-nitrosopiperidine (NPIP) and N-nitrosodibutylamine (NDBA).

Piktogramme

Exclamation markEnvironment
GHS07,GHS09

Signalwort

Warning

Gefahreneinstufungen

Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 3

Flammpunkt (°F)

147.2 °F - closed cup

Flammpunkt (°C)

64 °C - closed cup

Persönliche Schutzausrüstung

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
SHBL5904
422793/1
06819HE
05702TG
03412BO

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Dibutylsulfid ≥98.0% (GC)

Sigma-Aldrich

51491

Dibutylsulfid

Di-sec-butylsulfid 98%

Sigma-Aldrich

124311

Di-sec-butylsulfid

1-Benzothiophene for synthesis

Sigma-Aldrich

8.41538

1-Benzothiophene

Diallyldisulfid ≥98% (HPLC)

Sigma-Aldrich

SMB00378

Diallyldisulfid

Diethylsulfid 98%

Sigma-Aldrich

107247

Diethylsulfid

C Teyssier et al.
Drug metabolism and disposition: the biological fate of chemicals, 28(6), 648-654 (2000-05-23)
The metabolism of dipropyl disulfide (DPDS), an Allium sulfur compound, was investigated in rat liver cell subfractions and in an isolated perfused rat liver. DPDS is oxidized to dipropyl thiosulfinate (DPDSO) by rat microsomes. The contribution of cytochrome P450 enzymes
Han-Seung Shin et al.
Journal of agricultural and food chemistry, 50(26), 7684-7690 (2002-12-12)
Organosulfur compounds and sodium bisulfite significantly inhibited (P < 0.05) heterocyclic aromatic amine (HAA) formation in model systems containing phenylalanine, creatinine, and glucose. There was, however, no inhibition by the same compounds in a model system containing only phenylalanine and
S G Sundaram et al.
Biochimica et biophysica acta, 1315(1), 15-20 (1996-01-17)
Diallyl disulfide (DADS), an oil-soluble organosulfur compound in processed garlic, was more effective in inhibiting the in vitro growth of human tumor cell lines: HCT-15 (colon), A549 (lung), and SK MEL-2 (skin) than isomolar quantities of the water-soluble compound S-allyl
Opender Koul
Journal of economic entomology, 97(3), 1142-1147 (2004-07-29)
Head space volatiles, including 73% di-n-propyl disulfide, were collected from freshly crushed neem seeds. This compound along with previously reported diallyl disulfide (di-2-propenyl disulfide) were toxic when applied topically or as a fumigant to Tribolium castaneum adults and 8-, 12-
Małgorzata Iciek et al.
European journal of pharmacology, 569(1-2), 1-7 (2007-06-15)
The present in vivo studies demonstrated that diallyl disulfide (DADS), occurring in garlic, elevated hepatic sulfane sulfur level and activities of gamma-cystathionase and 3-mercaptopyruvate sulfotransferase in healthy mice but did not affect the hepatic glutathione level. DADS efficiently corrected the
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Protokolle

Protocols for the Fmoc SPPS of Cysteine-containing Peptides

Overcome challenges in synthesis and disulfide bond formation with protocols for Fmoc solid-phase peptide synthesis of peptides with cysteine and methionine.

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