Direkt zum Inhalt
Merck

HDAC6

histone deacetylase 6

Synonyme:
HD6
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(10013) Summary: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq, Jul 2008]
  • Mouse(15185) histone deacetylase 6
  • Rat(84581) histone deacetylase 6
  • Zebrafish(565482) histone deacetylase 6
  • domestic cat(101084086) histone deacetylase 6
  • cow(513602) histone deacetylase 6
  • dog(480907) histone deacetylase 6
  • fruit fly(32461) CG6170 gene product from transcript CG6170-RA
  • domestic guinea pig(100717988) histone deacetylase 6
  • naked mole-rat(101708442) histone deacetylase 6
  • sheep(101109245) histone deacetylase 6

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Monoclonal Anti-HDAC6 antibody produced in mouse, clone 1E2, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
western blot
Anti-HDAC6 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
dog, horse, human, pig, rabbit
Anwendung
ChIP
immunohistochemistry

western blot
Anti-HDAC6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-HDAC6 Antibody, CT, Upstate®, from rabbit,
Speziesreaktivität
human, mouse
Anwendung
immunoprecipitation (IP)
western blot
Anti-phospho-HDAC6 (pSer22) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunofluorescence

immunohistochemistry

western blot

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
SAHA, ≥98% (HPLC),
Spezies
human
Trichostatin A, ≥98% (HPLC), from Streptomyces sp.,
Spezies
human, mouse, rat
Romidepsin, ≥98% (HPLC),
Spezies
human
CI−994, ≥98% (HPLC), powder,
Spezies
human

Proteins

Produktnummer
Beschreibung
Spezies
HDAC-6 human, recombinant, expressed in baculovirus infected insect cells, ≥80% (SDS-PAGE),
Spezies
human
HDAC6 H216A human, recombinant, expressed in baculovirus infected Sf9 cells, ≥75% (SDS-PAGE),
Spezies
human
HDAC6 H611A human, recombinant, expressed in baculovirus infected Sf9 cells, ≥79% (SDS-PAGE),
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Hdac6,
Spezies
mouse
MISSION® esiRNA, targeting human HDAC6,
Spezies
human