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CL2B300

Sigma-Aldrich

Sepharose CL-2B Size Exclusion Resin

Cross-linked, 70-230 mesh

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
23151817
NACRES:
NA.56

product name

Sepharose CL-2B, Cross-linked

form

suspension

bead diameter

60-200 μm

pore size

100,000-20,000,000 fractionation range (Dextrans)
70,000-40,000,000 fractionation range (Globular proteins)

storage temp.

2-8°C

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General description

CL2B300-1L′s updated product number is GE17-0140-01

Application

Sepharose CL-2B is used in affinity chromatography, gel filtration chromatography, protein chromatography, separation media and resins. Sepharose CL-2B has been used to study ovarian carcinoma and cystic fibrosis.
Sepharose CL-2B has been used as resins in:
  • gel permeation chromatography (GPC)
  • gravity chromatography
  • streptavidin affinity chromatography
  • size exclusion chromatography

Legal Information

Sepharose is a trademark of Cytiva

Pictograms

Flame

Signal Word

Warning

Hazard Statements

Hazard Classifications

Flam. Liq. 3

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

102.2 °F - closed cup

Flash Point(C)

39 °C - closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Shyh-Dar Li et al.
Biochimica et biophysica acta, 1788(10), 2259-2266 (2009-07-15)
We have previously shown that the PEGylated LPD (liposome-polycation-DNA) nanoparticles were highly efficient in delivering siRNA to the tumor with low liver uptake. Its mechanism of evading the reticuloendothelial system (RES) is reported here. In LPD, nucleic acids were condensed
K Nakamura et al.
The Biochemical journal, 310 ( Pt 1), 263-269 (1995-08-15)
This study explores the role of cyclic nucleotides (i.e. cyclic AMP and cyclic GMP) in store-regulated external Ca2+ entry in human platelets. To stimulate store-regulated external Ca2+ entry, thapsigargin was used to deplete Ca2+ from the dense tubules, and sodium
R Bucki et al.
Biochemistry, 40(51), 15752-15761 (2001-12-19)
During platelet activation, phosphatidylserine (PS) exposure on the extracellular face of the plasma membrane is associated with increased procoagulant activity. PS externalization is generally attributed to an increase in intracellular Ca(2+). Various phospholipid transporters, such as specific scramblases or proteins
Extensive solubilization and depolymerization of cell wall polysaccharides during avocado (<I>Perseaamericana</I>) ripening involves concerted action of polygalacturonase and pectinmethylesterase.
Wakabayashi, K., et al.
Physiologia Plantarum, 108(4), 345-352 (2000)
H J Grimek et al.
Biology of reproduction, 30(2), 397-409 (1984-03-01)
Acetone precipitates of bovine follicular fluid from small (3-5 mm) and large (10-20 mm) follicles were fractionated by nondissociative procedures involving chromatography on Sephacryl S-300, DEAE cellulose, and Sepharose CL-2B. Most of the proteoglycan material eluted with a relatively low

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