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Key Documents

252565

Sigma-Aldrich

8-Hydroxyquinoline

ACS reagent, 98.5%

Synonym(s):

8-Quinolinol, 8-Hydroxyquinoline, 8-Oxychinolin, Oxine

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About This Item

Empirical Formula (Hill Notation):
C9H7NO
CAS Number:
Molecular Weight:
145.16
Beilstein:
114512
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.21

grade

ACS reagent

Quality Level

Assay

98.5%

ign. residue

≤0.05%

mp

72.5-74.0 °C

anion traces

sulfate (SO42-): ≤0.02%

antibiotic activity spectrum

fungi

Mode of action

DNA synthesis | interferes
enzyme | inhibits

SMILES string

Oc1cccc2cccnc12

InChI

1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H

InChI key

MCJGNVYPOGVAJF-UHFFFAOYSA-N

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General description

Chemical structure: quinolone

Application

8-Hydroxyquinoline may be used as a chelating ligand in the preparation of tris-(8-hydroxyquinoline)aluminum (Alq3), an organic electroluminescent compound used in organic light-emitting devices (OLEDs).

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Repr. 1B - Skin Sens. 1

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH Annex XVII (Restriction List)

CAS No.

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Preconcentration of trace elements in sea water by complexation with 8-hydroxyquinoline and adsorption on C18 bonded silica gel.
Watanabe H, et al.
Analytical Chemistry, 53(4), 738-739 (1981)
P Stephen Patrick et al.
Stem cell research & therapy, 11(1), 256-256 (2020-06-27)
MSCTRAIL is a cell-based therapy consisting of human allogeneic umbilical cord-derived MSCs genetically modified to express the anti-cancer protein TRAIL. Though cell-based therapies are typically designed with a target tissue in mind, delivery is rarely assessed due to a lack
Synthesis and characterization of tris-(8-hydroxyquinoline) aluminum
Li H, et al
Materials Science and Engineering, B, 100(1), 40-46 (2003)
Magdalena Polak-Berecka et al.
Journal of food science, 79(11), T2404-T2408 (2014-10-14)
The aim of this study was to assess the removal of Cd(2+) and Al(3+) from aqueous solutions by an exopolysaccharide (EPS) from Lactobacillus rhamnosus E/N. The biosorption kinetics of EPS for Cd(2+) and Al(3+) were studied by equilibrium dialysis after
Infra-red absorption spectra of metal chelates derived from 8-hydroxyquinoline, 2-methyl-8-hydroxyquinoline, and 4-methyl-8-hydroxyquinoline.
Charles RG, et al.
Spectrochimica Acta Part A: Molecular Spectroscopy, 8(1), 1-8 (1956)

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