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Key Documents

860562C

Avanti

18:1-12:0 Biotin PE

Avanti Polar Lipids 860562C

Synonym(s):

1-oleoyl-2-(12-biotinyl(aminododecanoyl))-sn-glycero-3-phosphoethanolamine

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About This Item

Empirical Formula (Hill Notation):
C45H83N4O10PS
CAS Number:
Molecular Weight:
903.20
UNSPSC Code:
12352211
NACRES:
NA.25

form

liquid

packaging

pkg of 1 × 1 mL (860562C-1mg)

manufacturer/tradename

Avanti Polar Lipids 860562C

concentration

1 mg/mL (860562C-1mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCCCCCCNC(CCCC[C@]1([H])SC[C@@]2([H])[C@]1([H])NC(N2)=O)=O)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O

InChI

1S/C45H83N4O10PS/c1-2-3-4-5-6-7-8-9-10-11-12-14-17-20-23-30-42(51)56-35-38(36-58-60(54,55)57-34-32-46)59-43(52)31-24-21-18-15-13-16-19-22-27-33-47-41(50)29-26-25-28-40-44-39(37-61-40)48-45(53)49-44/h9-10,38-40,44H,2-8,11-37,46H2,1H3,(H,47,50)(H,54,55)(H2,48,49,53)/b10-9-/t38-,39+,40+,44+/m1/s1

InChI key

HACDNRDNASOHSM-IBTAXAMTSA-N

Application

18:1-12:0 Biotin PE has been used:
  • as a ligand in phosphoethanolamine binding assay
  • in the generation of vesicle reconstituted with syntaxin-1A and Synaptosomal nerve-associated protein 25 (SNAP-25) vesicles
  • in the preparation of biotinylated liposomes

Biochem/physiol Actions

1-oleoyl-2-(12-biotinyl(aminododecanoyl))-sn-glycero-3-phosphoethanolamine, biotin PE is majorly used in the generation of lipid vesicle in supported lipid bilayer. It is also used in generation of phospholipid vesicle.

Packaging

5 mL Clear Glass Sealed Ampule (860562C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH Annex XVII (Restriction List)

CAS No.

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Molecular mechanisms of synaptic vesicle priming by Munc13 and Munc18
Lai Y, et al.
Neuron, 95(3), 591-607 (2017)
Factor VIII C1 domain residues Lys 2092 and Phe 2093 contribute to membrane binding and cofactor activity
Meems H, et al.
Blood, 114(18), 3938-3946 (2009)
TIRF imaging of Fc gamma receptor microclusters dynamics and signaling on macrophages during frustrated phagocytosis
Lin J, et al.
BMC Immunology, 17(1), 5-5 (2016)
Nolan C Worstell et al.
PloS one, 11(4), e0153265-e0153265 (2016-04-14)
Protein-glycan recognition is often mediated by multivalent binding. These multivalent bindings can be further complicated by cooperative interactions between glycans and individual glycan binding subunits. Here we have demonstrated a nanocube-based lipid bilayer array capable of quantitatively elucidating binding dissociation
Matthew Brecher et al.
Journal of virology, 86(1), 364-372 (2011-10-28)
Cellular entry of Ebola virus (EBOV), a deadly hemorrhagic fever virus, is mediated by the viral glycoprotein (GP). The receptor-binding subunit of GP must be cleaved (by endosomal cathepsins) in order for entry and infection to proceed. Cleavage appears to

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