545953
1-Aminohydantoin hydrochloride
98%
Synonym(s):
1-Amino-2,4-imidazolidinedione hydrochloride
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About This Item
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Assay
98%
mp
201-205 °C (lit.)
SMILES string
Cl[H].NN1CC(=O)NC1=O
InChI
1S/C3H5N3O2.ClH/c4-6-1-2(7)5-3(6)8;/h1,4H2,(H,5,7,8);1H
InChI key
WEOHANUVLKERQI-UHFFFAOYSA-N
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Application
1-Aminohydantoin hydrochloride may be used as one of the reactants in the synthesis of (E)-1-(2-hydroxybenzylideneamino)imidazolidine-2,4-dione, dantrolene and dantrolene sodium.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Synthesis of 1-Aminohydantoin Hydrochloride-(2-~(13) C,~(15) N_3) as Double Labeling Compound
Chemical World, 10, 015-015 (2012)
Crystal structure of (E)-1-(2-hydroxybenzylideneamino) imidazolidine-2, 4-dione, C10H9N3O3.
Zeitschrift fur Kristallographie, 230(2), 111-112 (2015)
Bioorganic & medicinal chemistry, 16(8), 4579-4588 (2008-03-04)
Peptide-semicarbazones derived from Z-Trp-Trp-Phe-aldehyde inhibit the chymotryptic activity of the human proteasome at nanomolar concentrations, but are less active in a NFkappaB reporter gene assay. Cyclic semicarbazones, in contrast, combine a strong inhibitory effect on the enzyme with an inhibition
Journal of medicinal chemistry, 30(2), 263-266 (1987-02-01)
A series of 1-[[[5-(substituted phenyl)-2-oxazolyl]methylene]amino]- 2,4-imidazolidinediones (6a-t) was synthesized, and the compounds were evaluated for direct skeletal muscle inhibition in the pithed rat gastrocnemius muscle preparation. The correctness of structural assignment of the new series was verified by alternate, unequivocal
Pharmaceutical Manufacturing Encyclopedia, 1-4, 1193-1193 (2013)
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