360627
Poly(vinyl alcohol)
Mw 9,000-10,000, 80% hydrolyzed
Synonym(s):
PAA
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form
crystals
mol wt
Mw 9,000-10,000
falling ball
2.5-3.5 cP, 4 % in H2O(20 °C)(lit.)
mp
250 °C (482 °F)
density
1.19-1.31 g/cm3
application(s)
advanced drug delivery
filtration
SMILES string
C=CO
InChI
1S/C2H4O/c1-2-3/h2-3H,1H2
InChI key
IMROMDMJAWUWLK-UHFFFAOYSA-N
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General description
PVA is a water soluble biocompatible polymer. It minimizes protein adsorption on its surface due to steric stabilization effect, unique solution properties and molecular conformation in aqueous form. The steric repulsion occurs due to osmotic pressure and elastic restoring forces competing with the van der Waal′s attraction between water soluble polymers and protein.
Application
PVA is used:
- In the cell collection medium for determining cellular function of mouse oocytes and eggs cells.
- As a coating and stabilizer in the preparation of drug loaded microparticles.
- In the preparation of biocompatible polymer blends of chitosan and poly (vinyl) alcohol.
- In the synthesis of bioactive polymer blends of poly(lactic acid)/poly(vinyl-alcohol)-chitosan.
- In developing chitosan-polyvinyl alcohol-bioactive glass composite membranes.
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
No data available
Flash Point(C)
No data available
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Journal of materials science. Materials in medicine, 20(2), 553-561 (2008-11-07)
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