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Key Documents

341584

Sigma-Aldrich

Poly(vinyl alcohol)

Mw 89,000-98,000, 99+% hydrolyzed

Synonym(s):

PVA

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About This Item

Linear Formula:
[-CH2CHOH-]n
CAS Number:
MDL number:
UNSPSC Code:
12352104
NACRES:
NA.23

Quality Level

form

powder

mol wt

Mw 89,000-98,000

falling ball

11.6-15.4 cP, 4 % in H2O(20 °C)(lit.)

mp

250 °C (482 °F)

density

1.19-1.31 g/cm3

application(s)

3D bioprinting
advanced drug delivery

SMILES string

C=CO

InChI

1S/C2H4O/c1-2-3/h2-3H,1H2

InChI key

IMROMDMJAWUWLK-UHFFFAOYSA-N

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General description

Polyvinyl alcohol (PVOH) is a hydrophilic linear polymer which forms copolymers of vinyl alcohol and vinyl acetate. Hence, the structural properties of polyvinyl alcohol polymers depend on the extent of polymerization and hydrolysis. Such changes cause both chemical and physical modifications such as esterification, etherification, crystallization, ion-polymer complexation in the polymer. Modified- PVOH structures are useful in biomedical applications.

Application

NaA zeolite particles have been dispersed in a poly(vinyl alcohol) matrix to prepare a mixed-matrix membrane to study the pervaporative separation of water-butanol mixtures. Poly (vinyl alcohol)/gelatin based biocompatible polymeric scaffolds have been used to design for 3D cancer models.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

No data available

Flash Point(C)

No data available

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Mixed-matrix membrane prepared from crosslinked PVA with NaA zeolite for pervaporative separation of water-butanol mixtures.
Duckkyu O, et al.
Desalination and Water Treatment, 51(25-27), 5362-5370 null
Polyvinyl Alcohol in Medicine and Pharmacy: A Perspective
Muppalaneni S and Omidian H
Journal of Developing Drugs, 2(3) (2013)
Interfacing polymeric scaffolds with primary pancreatic ductal adenocarcinoma cells to develop 3D cancer models
Ricci C, et al.
Biomatter (2014)
Chek Meng Poh et al.
Nature communications, 11(1), 2806-2806 (2020-06-03)
Given the ongoing SARS-CoV-2 pandemic, identification of immunogenic targets against the coronavirus spike glycoprotein will provide crucial advances towards the development of sensitive diagnostic tools and potential vaccine candidate targets. In this study, using pools of overlapping linear B-cell peptides
Ruobing Bai et al.
Macromolecular rapid communications, 40(8), e1800883-e1800883 (2019-02-12)
New applications of hydrogels draw growing attention to the development of tough hydrogels. Most tough hydrogels are designed through incorporating large energy dissipation from breaking sacrificial bonds. However, these hydrogels still fracture under prolonged cyclic loads with the presence of

Articles

In this article, we discuss issues critical to successful application of the electrospinning technique, including control of individual nanofibers to form secondary structures and assembly of nanofibers into 3D architectures.

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