Passa al contenuto
Merck

Aneuploid Cell Survival Relies upon Sphingolipid Homeostasis.

Cancer research (2017-08-05)
Yun-Chi Tang, Hui Yuwen, Kaiying Wang, Peter M Bruno, Kevin Bullock, Amy Deik, Stefano Santaguida, Marianna Trakala, Sarah J Pfau, Na Zhong, Tao Huang, Lan Wang, Clary B Clish, Michael T Hemann, Angelika Amon
ABSTRACT

Aneuploidy, a hallmark of cancer cells, poses an appealing opportunity for cancer treatment and prevention strategies. Using a cell-based screen to identify small molecules that could selectively kill aneuploid cells, we identified the compound

MATERIALI
N° Catalogo
Marchio
Descrizione del prodotto

Sigma-Aldrich
Anti-IgG di topo (molecola intera) - perossidasi, IgG fraction of antiserum, buffered aqueous solution
Sigma-Aldrich
Anti-Rabbit IgG (whole molecule)–Peroxidase antibody produced in goat, IgG fraction of antiserum, buffered aqueous solution
Sigma-Aldrich
Myriocin from Mycelia sterilia, ≥98% (HPLC), powder
Sigma-Aldrich
MISSION® esiRNA, targeting human SGMS1