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Key Documents

Z0292

Sigma-Aldrich

α-Zearalanol

~98% (HPLC), powder, mycotoxin

Sinonimo/i:

2,4-Dihydroxy-6-(6α,10-dihydroxyundecyl)benzoic acid μ-lactone

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About This Item

Formula empirica (notazione di Hill):
C18H26O5
Numero CAS:
Peso molecolare:
322.40
Numero CE:
Numero MDL:
Codice UNSPSC:
12352200
ID PubChem:
NACRES:
NA.77

product name

α-Zearalanol, ~98% (HPLC)

Origine biologica

synthetic (organic)

Livello qualitativo

Sterilità

non-sterile

Saggio

~98% (HPLC)

Forma fisica

powder

Controllo stupefacenti

regulated under CDSA - not available from Sigma-Aldrich Canada

tecniche

UHPLC: suitable

Solubilità

methanol: 1.96-2.04 mg/mL, clear, colorless to faintly yellow

Condizioni di spedizione

ambient

Temperatura di conservazione

−20°C

Stringa SMILE

C[C@H]1CCC[C@H](O)CCCCCc2cc(O)cc(O)c2C(=O)O1

InChI

1S/C18H26O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h10-12,14,19-21H,2-9H2,1H3/t12-,14+/m0/s1
DWTTZBARDOXEAM-GXTWGEPZSA-N

Pittogrammi

Health hazardCorrosion

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Repr. 2 - Skin Corr. 1B

Codice della classe di stoccaggio

8A - Combustible corrosive hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


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C Mastri et al.
Journal of steroid biochemistry, 23(3), 279-289 (1985-09-01)
It is now well established that the mycotoxin zearalenone and some of its derivatives possess oestrogenic activity. In the present study, the binding characteristics of [3H]zearalanol (P-1496) to different classes of sites including [1] the oestrogen receptor, [2] the higher
Angela Filannino et al.
Reproductive biology and endocrinology : RB&E, 9, 134-134 (2011-10-06)
The aim of this study was to investigate the in vitro effects of the Fusarium fungus-derived mycotoxin, zearalenone and its derivatives alpha-zearalenol and beta-zearalenol on motility parameters and the acrosome reaction of stallion sperm. Since the toxic effects of zearalenone
Shen Qu et al.
Environmental science & technology, 46(24), 13202-13211 (2012-11-21)
Trenbolone acetate, melengestrol acetate, and zeranol are synthetic hormones extensively used as growth promoters in animal agriculture, yet despite occurrence in water and soil little is known about their environmental fate. Here, we establish the time scales and mechanisms by
A Pazaiti et al.
International journal of clinical practice, 66(1), 28-36 (2011-12-08)
Zearalenone (ZEN) is a non-steroidal mycoestrogen that widely contaminates agricultural products. ZEN and its derivatives share similar molecular mechanisms and activity with estrogens and interact with ERα and ERβ leading to changes in the reproductive system in both animals and
Stefanie C Fleck et al.
Toxicology letters, 210(1), 9-14 (2012-01-31)
α-Zearalanol (α-ZAL, zeranol) is a highly estrogenic macrocyclic β-resorcylic acid lactone, which is used as a growth promotor for cattle in various countries. We have recently reported that α-ZAL and its major metabolite zearalanone (ZAN) are hydroxylated at the aromatic

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