Passa al contenuto
Merck
Tutte le immagini(5)

Key Documents

WH0004790M1

Sigma-Aldrich

Monoclonal Anti-NFKB1 antibody produced in mouse

clone 2E6, purified immunoglobulin, buffered aqueous solution

Sinonimo/i:

Anti-DKFZp686C01211, Anti-EBP1, Anti-KBF1, Anti-MGC54151, Anti-NFKBp105, Anti-NFKBp50, Anti-NFkappaB, Anti-nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Tutte le immagini(5)

About This Item

Numero MDL:
MFCD00802846
Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

mouse

Coniugato

unconjugated

Forma dell’anticorpo

purified immunoglobulin

Tipo di anticorpo

primary antibodies

Clone

2E6, monoclonal

Forma fisica

buffered aqueous solution

Reattività contro le specie

human

tecniche

indirect ELISA: suitable
indirect immunofluorescence: suitable
proximity ligation assay: suitable
western blot: 1-5 μg/mL

Isotipo

IgG1κ

N° accesso Genebanck

BC051765

N° accesso UniProt

P19838

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... NFKB1(4790)

Descrizione generale

NFKB1 (nuclear factor κB subunit 1) is a dimeric transcription factor. It belongs to the REL family. This gene is located on human chromosome 4q24.

Immunogeno

NFKB1 (AAH51765, 860 a.a. ~ 969 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MDNYEVSGGTVRELVEALRQMGYTEAIEVIQAASSPVKTTSQAHSLPLSPASTRQQIDELRDSDSVCDSGVETSFRKLSFTESLTSGASLLTLNKMPHDYGQEGPLEGKI

Azioni biochim/fisiol

NFKB1 (nuclear factor κB subunit 1) controls the maturation of NK (natural killer) cells and effector functions. This gene helps in the upregulation of intrauterine adhesion inflammatory factors, hence NFKB1 plays a major role in inflammatory diseases.

Stato fisico

Solution in phosphate buffered saline, pH 7.4

Note legali

GenBank is a registered trademark of United States Department of Health and Human Services

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Non trovi il prodotto giusto?  

Prova il nostro Motore di ricerca dei prodotti.

Raccomandato

N° Catalogo
Descrizione
Determinazione del prezzo

Codice della classe di stoccaggio

10 - Combustible liquids

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

EBV induces persistent NF-?B activation and contributes to survival of EBV-positive neoplastic T- or NK-cells
Takada H, et al.
PLoS ONE, 12(3) (2017)
NFKB1 regulates human NK cell maturation and effector functions
Lougaris V, et al.
Clinical Immunology (Orlando, Fla.) (2017)
Elevated NF-?B signaling in Asherman syndrome patients and animal models
Wang X, et al.
Oncotarget, 8(9), 15399-15406 (2017)
J Spring
FEBS letters, 400(1), 2-8 (1997-01-02)
For the growing fraction of human genes with identified functions there are often homologues known from invertebrates such as Drosophila. A survey of well established gene families from aldolases to zinc finger transcription factors reveals that usually a single invertebrate
Y Yu et al.
British journal of cancer, 111(3), 515-524 (2014-06-13)
Ovarian cancer has the highest mortality rate of the gynaecological cancers. Although cisplatin (CDDP) is an effective treatment for ovarian cancer, recurrence is frequent and leads to death. The objective was to explore the role and possible mechanisms of platelet-activating
Visualizza tutti i documenti correlati

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.