SRP5266

HDAC2, active, GST tagged human

recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

• Sinonimo/i: RPD3, YAF1
• Codice UNSPSC: 12352202
• NACRES: NA.32

Proprietà

• Ricombinante: expressed in baculovirus infected Sf9 cells
• Saggio: ≥70% (SDS-PAGE)
• Forma fisica: buffered aqueous glycerol solution
• Attività specifica: 3553-5520 RLU/min·ng
• PM: ~92 kDa
• N° accesso NCBI: NM_001527
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −70°C
• Informazioni sul gene: human ... HDAC2(3066)

Descrizione

Descrizione generale

HDAC2 or Histone deacetylase 2 belongs to the histone deacetylase family that acts via the formation of large multiprotein complexes, and is responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). HDAC2 forms transcriptional repressor complexes by associating with many different proteins and plays an important role in transcriptional regulation, cell cycle progression and developmental events. HDAC2 functions in modulating synaptic plasticity and long-lasting changes of neural circuits, which in turn negatively regulates learning and memory. HDAC1 and HDAC2 are functionally redundant in cardiac growth and development and they maintain cardiomyocyte identity and function.

Stato fisico

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

Nota sulla preparazione

After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable