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Documenti fondamentali

SRP4187

Sigma-Aldrich

IL-27 from mouse

recombinant, expressed in E. coli, ≥97% (SDS-PAGE), ≥97% (HPLC)

Sinonimo/i:

IL 27, Interleukin27

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About This Item

Codice UNSPSC:
12352202
NACRES:
NA.32

Origine biologica

mouse

Ricombinante

expressed in E. coli

Saggio

≥97% (HPLC)
≥97% (SDS-PAGE)

Stato

lyophilized

PM

~23.7 kDa

Confezionamento

pkg of 10 μg

Impurezze

endotoxin, tested

N° accesso NCBI

N° accesso UniProt

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

Informazioni sul gene

mouse ... Il27(246779)

Descrizione generale

Recombinant mouse IL-27/p28 Subunit, also known as Interleukin-30, is a member of the IL-12 family of Cytokines. When combined with EBI3 (Epstein-Barr virus induced gene 3), the heterodimer formed is IL-27. Mouse p28 is a proinflammatory cytokine inducing immunomodulatory effects. Current research is underway to delineate specific biological functions. Recombinant mouse p28 is a single-chain 207 amino acid peptide with a mass of approximately 23.7 kDa.

Stato fisico

Lyophilized from 10 mM NaP, pH 7.5.

Ricostituzione

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitute in water to a concentration of 0.1-1.0 μg/μL. The solution can then be diluted into other aqueous buffers.

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Juan Liao et al.
PloS one, 9(9), e108777-e108777 (2014-10-01)
The pathogenesis of complex diseases, such as type 1 diabetes (T1D), derives from interactions between host genetics and environmental factors. Previous studies have suggested that viral infection plays a significant role in initiation of T1D in genetically predisposed individuals. T1D

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