SRP3280

SCD27 LIGAND human

recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC)

• Sinonimo/i: CD70, TNFSF7
• Codice UNSPSC: 12352200
• NACRES: NA.32

Proprietà

• Origine biologica: human
• Ricombinante: expressed in CHO cells
• Saggio: ≥95% (HPLC); ≥95% (SDS-PAGE)
• Forma fisica: lyophilized
• Potenza: 10.0-25.0 ng/mL
• PM: 25.0-35.0 kDa
• Confezionamento: pkg of 50 μg
• Impurezze: <0.1 EU/μg endotoxin, tested
• Colore: white
• N° accesso UniProt: P32970
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• Informazioni sul gene: human ... CD70(970)

Descrizione

Descrizione generale

CD27 Ligand, a type II transmembrane protein, is expressed on activated T and B lymphocytes as well as NK cells. CD27L and its receptor (CD27) regulate the immune response by promoting T-cell expansion and differentiation, as well as NK enhancement. CD27 signaling can act as a co-stimulatory effector to sustain the survival of CD8+ T cells, primarily by inducing increased expression of the IL-2 gene.

Azioni biochim/fisiol

CD27 Ligand, a type II transmembrane protein, is a member of the TNF superfamily. Full length human CD27L is a 193 amino acid protein, consisting of a 17 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 155 amino acid extracellular domain. Human soluble CD27L corresponds to the 155 amino acid extracellular domain of the full length CD27L protein. Recombinant human sCD27L contains the extracellular domain plus an N-terminal His-Tag.

Stato fisico

Lyophilized from 20 mM Sodium Citrate, pH 3.0.

Ricostituzione

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable